Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483985 | 1.00 | HDAC8 (0.34) | HDAC8 | |
| Hydrochloric Acid SCHEMBL1151784 | 0.98 | HDAC8 (0.33) | HDAC8 | |
| Hydrochloric Acid SCHEMBL1151781 | 0.98 | HDAC8 (0.33) | HDAC8 | |
| SCHEMBL5196485 | 0.81 | HDAC8 (0.32) | HDAC8 | |
| Hydrochloric Acid SCHEMBL4805084 | 0.80 | HDAC8 (0.31) | HDAC8 | |
| SCHEMBL5197895 | 0.79 | KDM4E (0.45) | HDAC8 | |
| Hydrochloric Acid SCHEMBL4799280 | 0.78 | KDM4E (0.44) | — | |
| SCHEMBL839888 | 0.72 | HDAC8 (0.33) | HDAC8 | |
| Hydrochloric Acid SCHEMBL1152353 | 0.71 | HDAC8 (0.33) | HDAC8 | |
| Hydrochloric Acid SCHEMBL1152348 | 0.71 | HDAC8 (0.33) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072034-B2 | Process for lightening direct dyeing or oxidation dyeing in the presence of a particular organic amine, device therefore and anhydrous composition | L'ORÉAL (FR) | 2017-12-06 | — | — | EP | disclosed |
| EP-2198843-B1 | Lightening of human keratinic fibers with a anhydrous composition comprising a mixture of monoethanolamine/basic amine acid and kit | L'ORÉAL (FR) | 2017-09-13 | — | — | EP | disclosed |
| EP-2198833-B1 | Method of coloring or lightening of human keratinic fibers with an anhydrous composition and an inorganic base and kit | L'ORÉAL (FR) | 2017-07-26 | — | — | EP | disclosed |
| WO-2017109182-A1 | COMPOSITION COMPRISING AT LEAST TWO DIFFERENT STARCHES AND A COLOURING AGENT | L'OREAL (FR) | 2017-06-29 | — | — | WO | disclosed |
| EP-2198832-B1 | Method for lightening human keratinic fibers by applying an anhydrous composition and kit | L'ORÉAL (FR) | 2017-01-25 | — | — | EP | disclosed |
| WO-2016097126-A1 | COMPOSITION FOR DYEING OR LIGHTENING KERATIN FIBRES, IN THE FORM OF A MICROEMULSION BASED ON PARTICULAR OIL(S), HYDROTROPIC SOLVENTS AND SURFACTANT(S) | L'OREAL (FR) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016097123-A1 | COMPOSITION FOR DIRECT DYEING OF KERATIN FIBRES, IN THE FORM OF A MICROEMULSION BASED ON WATER, OIL(S) AND SURFACTANT(S) | L'OREAL (FR) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016097124-A1 | COMPOSITION FOR DYEING OR LIGHTENING KERATIN FIBRES, IN THE FORM OF A MICROEMULSION BASED ON OIL(S) AND SURFACTANT(S) | L'OREAL (FR) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016016441-A1 | COMPOSITION COMPRISING AN AMPS® COPOLYMER AND AN OXIDATION DYE PRECURSOR AND/OR A DIRECT DYE | L'OREAL (FR) | 2016-02-04 | — | — | WO | disclosed |
| EP-2248515-B1 | Use for dying keratinic fibers of a azomethine-type compound having a pyrazolopyridine group | ORÉAL L (FR) | 2015-12-23 | — | — | EP | disclosed |
| US-7288122-B2 | Cationic diazo compounds, compositions comprising them as direct dye, process for dyeing keratin fibers and device therefor | L'OREAL S.A. (FR) | 2007-10-30 | — | — | US | disclosed |
| US-7285138-B2 | Cationic diazo compound, compositions comprising at least one cationic diazo compound as a direct dye, a process for dyeing keratin fibers and device therefore | L'OREAL, S.A. (FR) | 2007-10-23 | — | — | US | disclosed |
| US-7282069-B2 | Cationic diazo compounds, compositions comprising them as direct dye, process for dyeing keratin fibers and device therefor | L'OREAL S.A. (FR) | 2007-10-16 | — | — | US | disclosed |
| US-7282069-B2 | Cationic diazo compounds, compositions comprising them as direct dye, process for dyeing keratin fibers and device therefor | L'OREAL S.A. (FR) | 2007-10-16 | — | — | US | disclosed |
| WO-2007110530-A2 | SPECIFIC DYES OF NAPHTHALIMIDE TYPE, DYEING COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USES | L'OREAL (FR) | 2007-10-04 | — | — | WO | disclosed |
| US-7247713-B2 | Symmetrical diazo compounds containing 2-pyridinium groups and cationic or non-cationic linker, compositions comprising them, method of coloring, and device | L'OREAL, S.A. (FR) | 2007-07-24 | — | — | US | disclosed |
| US-7208586-B2 | Cationic diazo compounds, compositions comprising them as direct dye, process for dyeing keratin fibers and device therefor | L'OREAL S.A. (FR) | 2007-04-24 | — | — | US | disclosed |
| US-20070044250-A1 | Cationic azo dyes with julolidine units, dyeing composition containing them, method of dyeing | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | disclosed |
| EP-1757264-A2 | Cationic julolidine comprising azo compounds, dyeing compositions and process for dyeing keratin fibres | L'Oréal (FR) | 2007-02-28 | — | — | EP | disclosed |
| US-20070010663-A1 | Dissymmetrical diazo compounds containing having at least one 2-imidazolium unit and a cationic or non-cationic linker, compositions comprising them, method of coloring, and device | L'OREAL S.A. (FR) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070044250-A1 | Cationic azo dyes with julolidine units, dyeing composition containing them, method of dyeing | KRT18, IK, ACR | HDAC8 2006/4885 |
| US-20070010663-A1 | Dissymmetrical diazo compounds containing having at least one 2-imidazolium unit and a cationic or non-cationic linker, compositions comprising them, method of coloring, and device | KRT18, DSP, DSG1 | HDAC8 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.