SCHEMBL484004

SCHEMBL484004

O=C(N=C=S)c1cccc(C(=O)N=C=S)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
FURIN P09958 1/20 0.37
MET P08581 1/20 0.36
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA6 P23280 1/20 0.34
CA9 Q16790 1/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
PARP1 P09874 1/20 0.33
PKM P14618 1/20 0.33
CTSL P07711 1/20 0.33
KMT2A Q03164 4/20 0.32
MEN1 O00255 3/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL571813 0.87 CES2 (0.55) L3MBTL1CES2CES1HDAC6PARP1
SCHEMBL3049569 0.87 PARP1 (0.52) TDP1HDAC8HDAC6PARP1CTSL
SCHEMBL3054202 0.87 PARP1 (0.52) L3MBTL1PARP1PKMKMT2AMEN1
SCHEMBL5824834 0.87 PARP1 (0.52) L3MBTL1TDP1PARP1KMT2AMEN1
SCHEMBL24728745 0.84 CES1 (0.44) L3MBTL1ATMTDP1CA12CA1
SCHEMBL8396 0.84 CES1 (0.44) L3MBTL1ATMTDP1CA12CA1
SCHEMBL1467416 0.84 GSK3B (0.53) KMT2AMEN1
SCHEMBL1616718 0.83 CES1 (0.42) L3MBTL1ATMTDP1CA12CA1
SCHEMBL23360898 0.83 CES1 (0.42) L3MBTL1ATMTDP1CA12CA1
SCHEMBL5824828 0.82 CES2 (0.59) CES2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100516038-C M-benzenedicarbonyl thioureas derivative, preparation and application thereof as fluorinion identification receptor UNIV NORTHWEST NORMAL (CN) 2009-07-22 CN claimed
CN-1919837-A m-benzenedicarbonyl thioureas derivative, preparation and application thereof as fluorinion identification receptor UNIV NORTHWEST NORMAL (CN) 2007-02-28 CN claimed
CN-121405676-A Double benzene ring diazole compound, emulsion type wax inhibitor and preparation method thereof 中国石油天然气股份有限公司 2026-01-27 CN disclosed
EP-3643735-B1 PHOTOCHROMIC POLYROTAXANE COMPOUND, AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC POLYROTAXANE COMPOUND TOKUYAMA CORP (JP) 2024-07-31 EP disclosed
EP-3779531-B1 PHOTOCHROMIC OPTICAL ARTICLE AND METHOD FOR MANUFACTURING SAME TOKUYAMA CORP (JP) 2024-03-20 EP disclosed
WO-2023210418-A1 THERMOSETTING COMPOSITION, CURED PRODUCT, AND OPTICAL MEMBER 富士フイルム株式会社 2023-11-02 WO disclosed
US-11767467-B2 Photochromic compound and curable composition containing said photochromic compound TOKUYAMA CORPORATION (JP) 2023-09-26 US disclosed
EP-3345954-B1 POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE TOKUYAMA CORP (JP) 2023-07-05 EP disclosed
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
EP-3653615-B1 CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION TOKUYAMA CORP (JP) 2023-03-01 EP disclosed
US-11578174-B2 Polyrotaxane, production method therefor, and optical composition containing said polyrotaxane TOKUYAMA CORPORATION (JP) 2023-02-14 US disclosed
US-5283312-A Colorless, transparent, high refractive index, heat resistance, low dispersion; polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-01 US disclosed
EP-0378895-B1 A MERCAPTO COMPOUND, A HIGH REFRACTIVE INDEX RESIN AND LENS AND A PROCESS FOR PREPARING THEM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-07-14 EP disclosed
EP-0549808-A1 TRANSPARENT PLASTIC MATERIAL SEIKO EPSON CORPORATION (JP) 1993-07-07 EP disclosed
US-5191055-A Polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-02 US disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed