SCHEMBL8396

SCHEMBL8396

O=C(N=C=S)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.44
CES2 O00748 5/20 0.44
ALDH1A1 P00352 3/20 0.44
TSHR P16473 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
TDP1 Q9NUW8 6/20 0.41
CA2 P00918 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
MAPT P10636 3/20 0.41
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA9 Q16790 3/20 0.41
CYP3A4 P08684 2/20 0.41
CA4 P22748 2/20 0.41
HSD17B10 Q99714 2/20 0.41
POLB P06746 1/20 0.41
PARP1 P09874 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24728745 1.00 CES1 (0.44) CES1CES2ALDH1A1TSHRDAO
SCHEMBL23360898 0.98 CES1 (0.42) CES1CES2ALDH1A1TSHRDAO
SCHEMBL1616718 0.98 CES1 (0.42) CES1CES2ALDH1A1TSHRDAO
SCHEMBL23360900 0.96 CA2 (0.41) CES1CES2ALDH1A1TSHRDAO
Acetone SCHEMBL28190449 0.94 CES2 (0.43) CES1CES2ALDH1A1TSHRDAO
Methylene Chloride SCHEMBL28208571 0.92 ALDH1A1 (0.45) CES1CES2ALDH1A1TSHRDAO
Acetonitrile SCHEMBL28134911 0.90 MAPT (0.38) CES1CES2ALDH1A1TSHRDAO
Benzoyl Chloride SCHEMBL8359124 0.90 CES1 (0.37) CES1CES2ALDH1A1TSHRDAO
SCHEMBL484049 0.88 TP53 (0.35) CES1CES2TSHRMAPTLMNA
SCHEMBL3184157 0.88 SMN1; SMN2 (0.48) ALDH1A1L3MBTL1MAPTLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5089 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059901-A 1,3, 4-Oxadiazole compound and preparation method and application thereof 成都大学 2026-05-19 CN claimed
US-12402638-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-09-02 US claimed
CN-115515998-B Synthesis of polyurethanes by chain growth copolymerization 伊夫·雅努 2025-06-24 CN claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119873919-A Formula production process and application method of macrobrachium rosenbergii seedling seawater 浙江省淡水水产研究所(浙江省淡水渔业环境监测站) 2025-04-25 CN claimed
CN-119768406-A Process for the preparation of substituted pyrrolopyrimidines and intermediates 阿斯利康(瑞典)有限公司 2025-04-04 CN claimed
CN-119638695-A Phenanthroline-substituted methyl guanidine compound, and preparation and application thereof 上海健康医学院 2025-03-18 CN claimed
WO-2025049604-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF MAZE THERAPEUTICS, INC. (US) 2025-03-06 WO claimed
US-12232516-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-02-25 US claimed
EP-0124282-A1 Bicyclooxyaryl thioureas and process for preparation UNION CARBIDE CORPORATION (US) 1984-11-07 EP claimed
EP-0113247-A1 Pesticidal phenoxyphenyl and phenoxypyridyl benzoyl ureas and process for their preparation UNION CARBIDE CORPORATION (US) 1984-07-11 EP claimed
EP-0098158-A1 Pesticidal 1-(alkyl-phenoxyaryl)-3-benzoyl ureas and process for preparation UNION CARBIDE CORPORATION (US) 1984-01-11 EP claimed
EP-0072954-A2 Isoindolin-2-yl-amino-imidazolines and isoindolin-2-yl guanidines, process for their preparation and their use as medicines Beiersdorf Aktiengesellschaft (DE) 1983-03-02 EP claimed
EP-0062844-A1 Substituted benzo(de)isoquinolines, processes for their preparation, and their application as pharmaceutical preparations Beiersdorf Aktiengesellschaft (DE) 1982-10-20 EP claimed
EP-0008435-B1 SUBSTITUTED N-PHENYL-N'-BENZOYL-THIOUREAS, THEIR PREPARATION AND THEIR USE AS PESTICIDES BAYER AG (DE) 1982-05-12 EP claimed
EP-0042732-A1 1-benzoyl-3-substituted ureas and thioureas, their preparation, insecticidal formulations containing them and their use as insecticides ELI LILLY AND COMPANY (US) 1981-12-30 EP claimed
EP-0039037-A1 Pyrimidylthio-ureas, medicines containing them and their use Beiersdorf Aktiengesellschaft (DE) 1981-11-04 EP claimed
EP-0008881-A1 1-Benzoyl-3-pyridinyl ureas, their use as insecticides, their preparation and formulations containing them ELI LILLY AND COMPANY (US) 1980-03-19 EP claimed
EP-0008435-A2 Substituted N-phenyl-N'-benzoyl-thioureas, their preparation and their use as pesticides BAYER AG (DE) 1980-03-05 EP claimed