SCHEMBL484027

SCHEMBL484027

Cc1ccc(N=C=O)c(SSc2cc(C)ccc2N=C=O)c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 4/20 0.44
▸ TRPA1 O75762 1/20 0.43
▸ HPGD P15428 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ NPC1 O15118 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ GAA P10253 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ TP53 P04637 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ ALOX15 P16050 1/20 0.35
▸ ALOX12 P18054 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ ADRA2A P08913 1/20 0.31
▸ CYP1A2 P05177 1/20 0.30
▸ CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466687 1.00 CYP3A4 (0.44) CYP3A4TRPA1HPGDALDH1A1TDP1
SCHEMBL3009802 0.89 CYP3A4 (0.44) CYP3A4TRPA1HPGDALDH1A1TDP1
SCHEMBL6848034 0.86 CYP3A4 (0.47) CYP3A4TRPA1HPGDALDH1A1TDP1
SCHEMBL27887506 0.85 CYP3A4 (0.41) CYP3A4TRPA1HPGDALDH1A1TDP1
SCHEMBL17847501 0.80 CYP3A4 (0.41) CYP3A4TRPA1HPGDALDH1A1TDP1
SCHEMBL645833 0.79 CYP3A4 (0.50) CYP3A4TRPA1HPGDALDH1A1TDP1
SCHEMBL30519851 0.79 CYP3A4 (0.50) CYP3A4TRPA1HPGDALDH1A1TDP1
SCHEMBL608937 0.78 CYP3A4 (0.48) CYP3A4TRPA1HPGDALDH1A1TDP1
SCHEMBL31115174 0.78 CYP3A4 (0.52) CYP3A4TRPA1HPGDALDH1A1TDP1
SCHEMBL31115173 0.78 CYP3A4 (0.52) CYP3A4TRPA1HPGDALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 553 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606692-B2 Spectacle lens HOYA LENS THAILAND LTD. (TH) 2026-04-21 — — US disclosed
EP-3983466-B1 AQUEOUS POLYURETHANE DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2026-02-18 — — EP disclosed
EP-3778170-B1 METHOD FOR MANUFACTURING OPTICAL MEMBER HOYA LENS THAILAND LTD (TH) 2026-01-28 — — EP disclosed
US-12384124-B2 Method for producing polarizing lens, polarizing film and polarizing lens HOYA LENS THAILAND LTD. (TH) 2025-08-12 — — US disclosed
EP-4396248-B1 AQUEOUS POLYURETHANE-UREA DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-08-06 — — EP disclosed
EP-3689932-B1 METHOD FOR MANUFACTURING OPTICAL MEMBER RESIN, OPTICAL MEMBER RESIN, SPECTACLE LENS, AND SPECTACLES HOYA LENS THAILAND LTD (TH) 2025-07-30 — — EP disclosed
US-12359016-B2 Method of preparing low haze polymer compositions for use in high refractive index optical materials PPG INDUSTRIES OHIO, INC. (US) 2025-07-15 — — US disclosed
US-20250188024-A1 METHOD OF PRODUCING PENTAERYTHRITOL MERCAPTOCARBOXYLATE, POLYMERIZABLE COMPOSITION, RESIN, OPTICAL MATERIAL, AND SPECTACLE LENS HOYA LENS THAILAND LTD. (TH) 2025-06-12 — — US disclosed
US-20250188215-A1 AQUEOUS POLYURETHANE DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-06-12 — — US disclosed
US-20250179014-A1 METHOD OF PRODUCING PENTAERYTHRITOL MERCAPTOCARBOXYLATE, POLYMERIZABLE COMPOSITION, RESIN, OPTICAL MATERIAL, AND SPECTACLE LENS HOYA LENS THAILAND LTD. (TH) 2025-06-05 — — US disclosed
US-5194559-A Reacting compounds containing isocyanate and isothiocyanate groups with polyol and polythiol; colorlrss, transparent MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-16 — — US disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 — — EP disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 — — EP disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 — — EP disclosed
US-5126388-A Sulfur-containing polyurethane or polythiourethane and internal mold release agent MITSUI TOATSU CHEMICALS, INC. (JP) 1992-06-30 — — US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 — — US disclosed
US-4946923-A S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-08-07 — — US disclosed
US-4929707-A Polyurethane base lens resin, plastic lens comprising the resin and preparation method of the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-05-29 — — US disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 — — EP disclosed
EP-0329389-A2 Polyurethane base lens and its preparation method MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606692-B2 Spectacle lens POT1, TCOF1, CRY1 CYP3A4 4631/4885TRPA1 871/4885HPGD 3959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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