Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4842803 | 0.92 | KMT2A (0.45) | DRD4KDM4EKMT2AHDAC3HDAC4 | |
| SCHEMBL4838750 | 0.92 | HRH4 (0.44) | NAMPTHRH4DHODHDRD4HTR2A | |
| Trifluoroacetic Acid SCHEMBL4844131 | 0.91 | HDAC6 (0.39) | HTR5ADHODHDRD4KMT2AHDAC3 | |
| SCHEMBL6220332 | 0.89 | HRH4 (0.41) | NAMPTHRH4DRD4HTR2AHTR2C | |
| Trifluoroacetic Acid SCHEMBL4846811 | 0.88 | ALDH1A1 (0.41) | DHODHMMP13KMT2AADRB1ADRB3 | |
| Trifluoroacetic Acid SCHEMBL4837280 | 0.88 | CDK4 (0.40) | DRD2DRD4DRD3KMT2AHDAC3 | |
| Trifluoroacetic Acid SCHEMBL4843769 | 0.87 | KMT2A (0.43) | HTR5AMMP13KDM4EKMT2AHDAC3 | |
| Trifluoroacetic Acid SCHEMBL4842215 | 0.87 | HDAC6 (0.41) | DRD2DRD4DRD3KMT2AHDAC6 | |
| Trifluoroacetic Acid SCHEMBL4840737 | 0.87 | HDAC6 (0.44) | KDM4EHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4839100 | 0.85 | PPARG (0.49) | DRD2DRD4ADRA1BDRD3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | HTR5A 3575/4885NAMPT 2385/4885HRH4 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.