Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5258414 | 0.93 | MEN1 (0.43) | ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL4842045 | 0.93 | ACHE (0.46) | ALDH1A1ACHEADRB1ADRB3MEN1 | |
| Trifluoroacetic Acid SCHEMBL4834190 | 0.92 | MEN1 (0.39) | MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4844087 | 0.89 | MEN1 (0.51) | ADRB1ADRB3MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4840541 | 0.88 | HTR5A (0.42) | ADRB1ADRB3DHODHMMP13KMT2A | |
| Trifluoroacetic Acid SCHEMBL4846277 | 0.88 | KMT2A (0.42) | ALDH1A1ADRB1ADRB3MMP13MEN1 | |
| Trifluoroacetic Acid SCHEMBL4844245 | 0.88 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL4838763 | 0.86 | MEN1 (0.42) | ADRB1ADRB3MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5260635 | 0.85 | — | — | |
| Trifluoroacetic Acid SCHEMBL4845402 | 0.85 | MEN1 (0.39) | ADRB1ADRB3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | ALDH1A1 1489/4885ACHE 1390/4885ADRB1 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.