Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777081 | 0.95 | ADRB3 (0.42) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4776666 | 0.95 | ADRB3 (0.42) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4645453 | 0.90 | ADRB3 (0.45) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4640763 | 0.90 | ADRB3 (0.45) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4894075 | 0.89 | ADRB3 (0.43) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4640303 | 0.88 | ADRB3 (0.47) | ADRB3HPGDNR1I2ALDH1A1OPRM1 | |
| SCHEMBL4643457 | 0.88 | ADRB3 (0.47) | ADRB3HPGDNR1I2ALDH1A1OPRM1 | |
| SCHEMBL4775581 | 0.88 | ADRB3 (0.42) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4773319 | 0.88 | ADRB3 (0.42) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4832542 | 0.88 | ADRB3 (0.40) | ADRB3ADRB2ADRB1HPGDNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945304-A2 | IMIDAZO-PYRIDINE CONTAINING BETA AGONISTS, METHOD FOR PRODUCING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007048843-A2 | IMIDAZO-PYRIDINE CONTAINING BETA AGONISTS, METHOD FOR PRODUCING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-03 | — | — | WO | disclosed |