Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4840464 | 0.94 | TRPA1 (0.39) | TRPA1MAPTMMP1MMP9MMP13 | |
| SCHEMBL4838499 | 0.94 | TRPA1 (0.37) | TRPA1MAPTMMP1MMP9MMP13 | |
| SCHEMBL4837504 | 0.94 | TRPA1 (0.36) | TRPA1MMP1MMP9MMP13ADAM17 | |
| SCHEMBL4839596 | 0.92 | POLB (0.36) | TRPA1MAPTMMP1MMP9MMP13 | |
| SCHEMBL4832976 | 0.92 | MAPT (0.39) | TRPA1MAPTMMP1MMP9MMP13 | |
| SCHEMBL4838813 | 0.92 | MMP8 (0.40) | TRPA1MAPTMMP1MMP9MMP13 | |
| SCHEMBL4840502 | 0.89 | MAPT (0.39) | TRPA1MAPTPOLBRORCMAPK1 | |
| SCHEMBL4839598 | 0.88 | MAPT (0.39) | TRPA1MAPTMMP1MMP9MMP13 | |
| SCHEMBL4845391 | 0.88 | TRPA1 (0.37) | TRPA1MMP1MMP9MMP13ADAM17 | |
| SCHEMBL4841609 | 0.88 | TRPA1 (0.36) | TRPA1MAPTMMP1MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |