SCHEMBL484109

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13189539	0.86	CYP1A2 (0.41)	POLBCYP1A2HTT
	SCHEMBL12402832	0.84	LMNA (0.36)	CXCL8NOD1KMT2AHTTDRD2
	SCHEMBL27961016	0.83	KDM4E (0.36)	POLBNOD1KMT2AHTT
	SCHEMBL12324755	0.83	GRM5 (0.41)	CXCR4POLBKMT2ACYP1A2CYP2D6
	SCHEMBL12324107	0.81	PIK3CA (0.43)	PIK3CACYP1A2CYP2D6
	SCHEMBL2804309	0.79	KDM4E (0.41)	POLBKMT2ACYP1A2CYP2D6HTT
	SCHEMBL12324086	0.78	APP (0.40)	POLBKMT2AHTT
	SCHEMBL27894583	0.78	LMNA (0.41)	CXCR4POLBKMT2ACYP1A2CYP2D6
	SCHEMBL484685	0.77	ALDH1A1 (0.47)	POLBKMT2ACYP1A2HTT
	SCHEMBL12403519	0.77	ALDH1A1 (0.47)	POLBKMT2ACYP1A2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.