SCHEMBL484138

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL484127	0.74	KDM4E (0.48)	KDM4EALDH1A1SMN1; SMN2NPSR1LMNA
	SCHEMBL5539722	0.73	KDM4E (0.69)	KDM4EALDH1A1SMN1; SMN2NPSR1LMNA
	SCHEMBL12324747	0.73	KDM4E (0.49)	KDM4EALDH1A1SMN1; SMN2NPSR1LMNA
	SCHEMBL12469920	0.72	KDM4E (0.45)	KDM4EALDH1A1SMN1; SMN2DRD2DRD3
	SCHEMBL484301	0.72	KDM4E (0.47)	KDM4EALDH1A1SMN1; SMN2DRD2DRD3
	SCHEMBL12469964	0.71	JAK2 (0.52)	KDM4EALDH1A1SMN1; SMN2NPSR1LMNA
	SCHEMBL2162731	0.71	KDM4E (0.48)	KDM4EALDH1A1SMN1; SMN2NPSR1LMNA
	SCHEMBL12403403	0.71	HPGD (0.52)	KDM4EALDH1A1SMN1; SMN2NPSR1LMNA
	SCHEMBL12324097	0.71	KDM4E (0.73)	KDM4EALDH1A1SMN1; SMN2NPSR1LMNA
	SCHEMBL2163406	0.70	JAK2 (0.54)	KDM4EALDH1A1SMN1; SMN2DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.