SCHEMBL484301

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12324747	0.81	KDM4E (0.49)	KDM4EALDH1A1NPSR1GAALMNA
	SCHEMBL484251	0.78	KDM4E (0.71)	KDM4EALDH1A1NPSR1GAALMNA
	SCHEMBL2163406	0.78	JAK2 (0.54)	KDM4EALDH1A1NPSR1GAALMNA
	SCHEMBL12469920	0.78	KDM4E (0.45)	KDM4EALDH1A1NPSR1GAALMNA
	SCHEMBL12402915	0.78	MYC (0.58)	KDM4EALDH1A1NPSR1GAALMNA
	SCHEMBL12469964	0.77	JAK2 (0.52)	KDM4EALDH1A1NPSR1GAALMNA
	SCHEMBL12403403	0.76	HPGD (0.52)	KDM4EALDH1A1NPSR1GAALMNA
	SCHEMBL12324097	0.76	KDM4E (0.73)	KDM4EALDH1A1NPSR1GAALMNA
	SCHEMBL12467962	0.75	CYP11B2 (0.54)	KDM4EALDH1A1GAAHPGDTP53
	SCHEMBL484127	0.74	KDM4E (0.48)	KDM4EALDH1A1NPSR1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.