SCHEMBL4841543

SCHEMBL4841543

CC=CC(=O)O[Si](C)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28470791 0.88 KEAP1 (0.33) HCAR2KEAP1NFE2L2
SCHEMBL3619133 0.80
SCHEMBL27710287 0.80 ALDH1A1 (0.32)
SCHEMBL28238500 0.80
SCHEMBL259944 0.79 HCAR2 (0.36) HCAR2KEAP1NFE2L2
SCHEMBL743851 0.78 KEAP1 (0.33) HCAR2KEAP1NFE2L2
SCHEMBL743850 0.78 KEAP1 (0.33) HCAR2KEAP1NFE2L2
SCHEMBL27730626 0.77 HCAR2 (0.32) HCAR2
SCHEMBL27730778 0.77 HCAR2 (0.32) HCAR2
SCHEMBL2584602 0.74 TSHR (0.35) HCAR2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101646718-B Curable resin composition, protective film, and method for forming protective film JSR CORP JP 2013-04-03 CN disclosed
CN-101646718-A The formation method of curable resin composition, protective membrane and protective membrane JSR CORP JP 2010-02-10 CN disclosed
CN-101226329-A Radiation sensitive resin composition, laminated insulating film, micro lens and preparation method thereof JSR CORP (JP) 2008-07-23 CN disclosed
US-7361407-B2 Stain resistant coating compositions, methods of coating and coated articles BASF COATINGS JAPAN LTD. (JP) 2008-04-22 US disclosed
US-20040202873-A1 Stain resistant coating compositions, methods of coating and coated articles BASF NOF COATINGS CO., LTD. 2004-10-14 US disclosed
US-6797391-B2 WHICH CAN GIVE PAINT FILM MANIFESTING HIGH DEGREE OF HYDROPHILIC PROPERTY, WHICH HAS A FUNCTION OF CLEANING THE STAINED AUTOMOBILE BY SELF WASHING WITH RAIN BASF NOF COATINGS CO., LTD. (JP) 2004-09-28 US disclosed
CN-1131279-C Durable water repellent and coated articles DAIKIN IND LTD (JP) 2003-12-17 CN disclosed
US-20030040561-A1 Nonstaining coating compositions, method of finish coating, and coated articles BASF JAPAN LTD. (JP) 2003-02-27 US disclosed
CN-1237991-A Durable water repellent and coated articles DAIKIN IND LTD (JP) 1999-12-08 CN disclosed