Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 6/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.36 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.36 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924840 | 0.76 | HSD17B1 (0.43) | HPGDSPIK3CDPIK3CBPIM1GSK3B | |
| SCHEMBL4841899 | 0.72 | HPGDS (0.42) | HPGDSPIK3CDPIK3CBPIM1GSK3B | |
| SCHEMBL3931939 | 0.67 | PIK3CD (0.54) | HPGDSPIK3CDPIK3CBPIM1GSK3B | |
| SCHEMBL3928704 | 0.66 | PIK3CD (0.52) | HPGDSPIK3CDPIK3CBPIM1GSK3B | |
| SCHEMBL3928762 | 0.66 | HPGDS (0.47) | HPGDSPIK3CDPIK3CBPIM1GSK3B | |
| SCHEMBL3929341 | 0.65 | PIK3CD (0.48) | HPGDSPIK3CDPIK3CBPIM1GSK3B | |
| SCHEMBL3931589 | 0.65 | ASH1L (0.43) | HPGDSPIK3CDPIK3CBPIM1GSK3B | |
| SCHEMBL3928021 | 0.65 | PIK3CD (0.50) | HPGDSPIK3CDPIK3CBPIM1GSK3B | |
| SCHEMBL3928814 | 0.65 | PIK3CD (0.47) | HPGDSPIK3CDPIK3CBPIM1GSK3B | |
| SCHEMBL3931091 | 0.64 | PIK3CD (0.49) | HPGDSPIK3CDPIK3CBPIM1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008059-A1 | ANTI-CANCER AGENTS ANS USES THEREOF | LOCUS PHARMACEUTICALS, INC. (US) | 2008-01-17 | — | — | WO | disclosed |