SCHEMBL484207

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20777186	0.87	SMN1; SMN2 (0.50)	NPC1RAB9AKDM4EGAAALDH1A1
	SCHEMBL6854044	0.76	SMN1; SMN2 (0.52)	NPC1RAB9AKDM4EGAAALDH1A1
	SCHEMBL484157	0.75	APP (0.49)	NPC1RAB9AKDM4EGAAALDH1A1
	SCHEMBL5811772	0.75	SMN1; SMN2 (0.47)	NPC1RAB9AKDM4EGAAALDH1A1
	SCHEMBL31337216	0.74	SMN1; SMN2 (0.50)	NPC1RAB9AKDM4EGAAALDH1A1
	SCHEMBL6852080	0.72	SMN1; SMN2 (0.47)	NPC1RAB9AKDM4EGAAALDH1A1
	SCHEMBL6847971	0.72	SMN1; SMN2 (0.47)	NPC1RAB9AKDM4EALDH1A1TP53
	SCHEMBL23704415	0.72	SMN1; SMN2 (0.55)	NPC1RAB9AKDM4EGAAALDH1A1
	SCHEMBL1997873	0.72	PSMB8 (0.56)	NPC1RAB9AKDM4EGAAALDH1A1
	SCHEMBL20448743	0.72	SMN1; SMN2 (0.55)	NPC1RAB9AKDM4EGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.