SCHEMBL484157

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL485717	0.78	NPC1 (0.43)	NPC1RAB9ASMN1; SMN2TP53L3MBTL1
	SCHEMBL12324753	0.78	APP (0.60)	APPNPC1RAB9ASMN1; SMN2TP53
	SCHEMBL20777186	0.77	SMN1; SMN2 (0.50)	NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1
	SCHEMBL12324086	0.76	APP (0.40)	APPNPC1RAB9ASMN1; SMN2TP53
	SCHEMBL484207	0.75	NPC1 (0.55)	APPNPC1RAB9ASMN1; SMN2TP53
	SCHEMBL483811	0.73	TTR (0.45)	APPNPC1RAB9ASMN1; SMN2TP53
	SCHEMBL484346	0.71	BCHE (0.42)	APPNPC1RAB9ASMN1; SMN2TP53
	SCHEMBL12402793	0.70	APP (0.54)	APPNPC1RAB9ASMN1; SMN2TP53
	SCHEMBL5811772	0.69	SMN1; SMN2 (0.47)	NPC1RAB9ASMN1; SMN2TP53ALDH1A1
	SCHEMBL484685	0.68	ALDH1A1 (0.47)	APPNPC1RAB9ASMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.