SCHEMBL484215

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4851268	0.82	NPC1 (0.46)	NPC1RAB9AMEN1KMT2AAR
	SCHEMBL240431	0.81	NPC1 (0.63)	NPC1RAB9AMEN1KMT2AAR
	SCHEMBL34467584	0.81	NPC1 (0.63)	NPC1RAB9AMEN1KMT2AAR
	SCHEMBL2275275	0.80	AHR (0.62)	NPC1CA1CA2AHRGUSB
	SCHEMBL4337601	0.79	NPC1 (0.61)	NPC1RAB9AMEN1KMT2AAR
	SCHEMBL2220158	0.79	NPC1 (0.61)	NPC1RAB9AMEN1KMT2AAR
	SCHEMBL12112870	0.76	RAB9A (0.80)	NPC1RAB9AMEN1KMT2AAR
	SCHEMBL21250701	0.76	NPC1 (0.60)	NPC1CYP3A4CYP2D6CA1CA2
	SCHEMBL12403165	0.76	RAB9A (0.50)	NPC1RAB9AMEN1KMT2AAR
	SCHEMBL1365652	0.76	NPC1 (0.58)	NPC1RAB9AMEN1KMT2AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.