SCHEMBL4842664

SCHEMBL4842664

Nc1cccc(Oc2ccc(C(F)(c3ccc(Oc4cccc(N)c4)cc3)C(F)(F)C(F)(F)F)cc2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.56
ALDH1A1 P00352 5/20 0.49
MAPT P10636 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
MITF O75030 1/20 0.49
GAA P10253 1/20 0.49
GFER P55789 1/20 0.49
NLRP1 Q9C000 1/20 0.49
NOD2 Q9HC29 1/20 0.49
POLB P06746 1/20 0.46
HSP90AA1 P07900 1/20 0.46
ATM Q13315 1/20 0.43
LTA4H P09960 1/20 0.42
MAPK1 P28482 2/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29007641 0.92 ALDH1A1 (0.49) MAOBALDH1A1MAPTSMN1; SMN2MEN1
Orthotolidine SCHEMBL29129033 0.86 MAOB (0.42) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL28621904 0.84 ALDH1A1 (0.58) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL127744 0.84 MAOB (0.59) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL9578280 0.84 MAOB (0.59) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL29390225 0.84 MAOB (0.59) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL29371179 0.84 MAOB (0.59) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL4703990 0.83 MAOB (0.63) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL30098473 0.83 MAOB (0.63) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL2403728 0.83 ALDH1A1 (0.55) MAOBALDH1A1MAPTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047948-A Resin, preparation method thereof and resin composition 华为技术有限公司 2024-05-17 CN claimed
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN claimed
CN-117304037-A Diamine monomer, preparation method thereof, resin and application thereof 华为技术有限公司 2023-12-29 CN claimed
CN-114395215-A Sulfone ether epoxy adhesive and UHMWPE fiber reinforced bulletproof composite material and preparation method thereof 兰溪聪普新材料有限公司 2022-04-26 CN claimed
CN-109705799-B YASI epoxy organic imide silica gel and preparation method thereof 东华大学 2022-03-18 CN claimed
CN-114015044-A Colorless transparent polyimide resin film and preparation method thereof 山东中柔新材料有限公司 2022-02-08 CN claimed
CN-109852330-B 3, 5-diaminobenzoic acid type silicon-containing adhesive and preparation method thereof 东华大学 2022-01-11 CN claimed
CN-109735295-B Imide organic silica gel and preparation method thereof 福建省海钛智能科技有限公司 2021-12-28 CN claimed
CN-109722212-B Imide epoxy organic silica gel and preparation method thereof 福建省海钛智能科技有限公司 2021-12-28 CN claimed
CN-109852340-B YASI-BDAPOFP type organic fluorosilicone adhesive and preparation method thereof 福建省海钛智能科技有限公司 2021-12-28 CN claimed
CN-109852331-B 3, 5-bis (4-aminophenoxy) benzoic acid type organic silica gel and preparation method thereof 福建省海钛智能科技有限公司 2021-12-28 CN claimed
CN-110016138-B High-flame-retardancy polyimide film and preparation method thereof 东华大学 2021-11-09 CN claimed
CN-109942815-B Polyimide composite resin with low dielectric constant, preparation method and application 浙江福斯特新材料研究院有限公司 2021-06-01 CN claimed
CN-111410891-A Self-adhesive corona-resistant polyimide paint, enameled wire and preparation method thereof 苏州巨峰电气绝缘系统股份有限公司 2020-07-14 CN claimed
CN-111393949-A Self-adhesive paint, corona-resistant polyimide paint and preparation method thereof 苏州巨峰电气绝缘系统股份有限公司 2020-07-10 CN claimed
CN-111138695-A Polyimide film and preparation method thereof 深圳先进电子材料国际创新研究院 2020-05-12 CN claimed
CN-110698644-A Phthalimide glycidyl ester epoxy resin and preparation method thereof 东华大学 2020-01-17 CN claimed
CN-110591293-A Carbon fiber cable core pultrusion resin and preparation method thereof 东华大学 2019-12-20 CN claimed
WO-2024262811-A1 COMPOSITION FOR ELECTRODEPOSITION COATING OF IMIDE-BASED POLYMER FOR CONTROLLING FILM THICKNESS AND SUPPRESSING BUBBLE FORMATION, AND ELECTRODEPOSITION COATING METHOD USING SAME 한국전기연구원 2024-12-26 WO disclosed
EP-0299865-A2 Process for preparing low dielectric polyimides NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1989-01-18 EP disclosed