SCHEMBL127744

SCHEMBL127744

Nc1cccc(Oc2ccc(C(c3ccc(Oc4cccc(N)c4)cc3)(C(F)(F)F)C(F)(F)F)cc2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.59
ALDH1A1 P00352 6/20 0.52
MAPT P10636 4/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
MITF O75030 1/20 0.52
GAA P10253 1/20 0.52
GFER P55789 1/20 0.52
NLRP1 Q9C000 1/20 0.52
NOD2 Q9HC29 1/20 0.52
POLB P06746 1/20 0.49
HSP90AA1 P07900 1/20 0.49
ATM Q13315 1/20 0.45
LTA4H P09960 1/20 0.43
CYP3A4 P08684 3/20 0.43
MAPK1 P28482 2/20 0.43
TSHR P16473 2/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390225 1.00 MAOB (0.59) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL29371179 1.00 MAOB (0.59) MAOBALDH1A1MAPTSMN1; SMN2MEN1
Ammonia Solution, Strong SCHEMBL8591863 0.98 MAOB (0.58) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL9742335 0.97 ALDH1A1 (0.58) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL3465565 0.97 ALDH1A1 (0.58) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL10583295 0.95 MAOB (0.54) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL6402981 0.89 MAOB (0.51) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL29007641 0.89 ALDH1A1 (0.49) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL31105162 0.89 MAOB (0.51) MAOBALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL250124 0.88 MAOB (0.56) MAOBALDH1A1MAPTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1762 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132262-A1 BLACK POLYIMIDE FILM AND THE MANUFACTURING METHOD THEREOF PI ADVANCED MAT CO LTD (KR) 2026-05-14 US claimed
US-20260132256-A1 POLYAMIC ACID COMPOSITION AND POLYIMIDE PREPARED WITH THE SAME PI ADVANCED MAT CO LTD (KR) 2026-05-14 US claimed
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM PI ADVANCED MAT CO LTD (KR) 2026-05-07 US claimed
US-20260092194-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF PI ADVANCED MAT CO LTD (KR) 2026-04-02 US claimed
EP-4714998-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME PI Advanced Materials Co., Ltd. (KR) 2026-03-25 EP claimed
US-20260062517-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME PI ADVANCED MAT CO LTD (KR) 2026-03-05 US claimed
US-12522704-B2 Polyimide film having high dimensional stability and manufacturing method therefor PI ADVANCED MATERIALS CO., LTD. (KR) 2026-01-13 US claimed
US-20260008935-A1 POLYIMIDE FILM AND MANUFACTURING METHOD THEREFOR PL ADVANCED MAT CO LTD (KR) 2026-01-08 US claimed
US-12503596-B2 Low-dielectric-constant polyimide composite powder, and method for producing same PI ADVANCED MATERIALS CO., LTD. 2025-12-23 US claimed
EP-4626991-A1 POLYIMIDE VARNISH FOR COATING CONDUCTOR WITH IMPROVED HEAT DISSIPATION FOR COATING CONDUCTOR AND POLYIMIDE COATING MATERIAL COMPRISING THE SAME PI Advanced Materials Co., Ltd. (KR) 2025-10-08 EP claimed
US-4895972-A Process for lowering the dielectric constant of polyimides using diamic acid additives THE UNITED STATES OF AMERICAN AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1990-01-23 US claimed
US-4892896-A LIQUEFACTION WITH MICROWAVE RADIATION, FLUORINE CONTAINING DIAMINES ETHYL CORPORATION (US) 1990-01-09 US claimed
US-4877653-A HEAT ANNEALING HOECHST CELANESE CORPORATION (US) 1989-10-31 US claimed
EP-0336374-A2 Processing polyimide precursor compositions ETHYL CORPORATION (US) 1989-10-11 EP claimed
US-4859530-A High temperature adhesive for polymide films ETHYL CORPORATION (US) 1989-08-22 US claimed
EP-0317941-A2 Photosensitive polyimide polymer compositions HOECHST CELANESE CORPORATION (US) 1989-05-31 EP claimed
US-4803147-A Photosensitive polyimide polymer compositions HOECHST CELANESE CORPORATION (US) 1989-02-07 US claimed
EP-0299865-A2 Process for preparing low dielectric polyimides NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1989-01-18 EP claimed
EP-0298668-A2 High temperature adhesive for polyimide films and its use ETHYL CORPORATION (US) 1989-01-11 EP claimed
EP-0287355-A2 Polyimide precursors, their use and formation ETHYL CORPORATION (US) 1988-10-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132262-A1 BLACK POLYIMIDE FILM AND THE MANUFACTURING METHOD THEREOF PARG, PARN, DYNC1LI1 MAOB 2752/4885ALDH1A1 1618/4885MAPT 440/4885
US-20260092194-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF SMURF1, TET1, VCL MAOB 4532/4885ALDH1A1 3169/4885MAPT 1398/4885
US-20260062517-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME AOC1, AOC2, DDT MAOB 123/4885ALDH1A1 40/4885MAPT 2952/4885
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM CDH1, PBRM1, ITGA1 MAOB 4154/4885ALDH1A1 228/4885MAPT 2652/4885
US-20260008935-A1 POLYIMIDE FILM AND MANUFACTURING METHOD THEREFOR MALT1, CDH1, TET1 MAOB 2249/4885ALDH1A1 1801/4885MAPT 536/4885
US-20260132256-A1 POLYAMIC ACID COMPOSITION AND POLYIMIDE PREPARED WITH THE SAME PARG, PARN, PUF60 MAOB 2585/4885ALDH1A1 1975/4885MAPT 403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.