Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | PDE6D | O43924 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469964 | 0.86 | JAK2 (0.52) | CYP11B1MAPTHPGDKDM4EPDE6D | |
| SCHEMBL28902001 | 0.85 | CYP11B2 (0.58) | CYP11B2CYP11B1MAPTHPGDKDM4E | |
| SCHEMBL29411940 | 0.85 | CYP11B2 (0.58) | CYP11B2CYP11B1MAPTHPGDKDM4E | |
| SCHEMBL12116699 | 0.83 | CYP11B2 (0.70) | CYP11B2CYP11B1MAPTHPGDKDM4E | |
| SCHEMBL29411897 | 0.81 | ALDH1A1 (0.76) | CYP11B2MAPTHPGDKDM4EPDE6D | |
| SCHEMBL13668118 | 0.80 | MAPT (0.55) | CYP11B2CYP11B1MAPTNOS2HPGD | |
| SCHEMBL16604025 | 0.80 | MAPT (0.62) | CYP11B2CYP11B1MAPTNOS2KDM4E | |
| SCHEMBL29076122 | 0.80 | KDM4E (0.65) | CYP11B2CYP11B1MAPTNOS2HPGD | |
| SCHEMBL30581241 | 0.80 | KDM4E (0.65) | CYP11B2CYP11B1MAPTNOS2HPGD | |
| SCHEMBL13668123 | 0.79 | MAPT (0.54) | CYP11B2CYP11B1MAPTNOS2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110182812-A1 | Imaging Agents for Detecting Neurological Disorders | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-07-28 | — | — | US | disclosed |
| US-20100239496-A1 | Imaging agents for detecting neurological disorders | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182812-A1 | Imaging Agents for Detecting Neurological Disorders | MAPT, APP, PSEN1 | CYP11B2 3021/4885CYP11B1 3035/4885MAPT 1/4885 |
| US-20100239496-A1 | Imaging agents for detecting neurological disorders | MAPT, APP, PSEN1 | CYP11B2 2883/4885CYP11B1 2597/4885MAPT 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.