Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15471105 | 0.87 | GPR35 (0.38) | RAB9ANPC1PGRESR1GPR35 | |
| SCHEMBL15466178 | 0.87 | GPR35 (0.38) | RAB9ANPC1PGRESR1GPR35 | |
| SCHEMBL15466208 | 0.85 | NPC1 (0.35) | RAB9ANPC1PGRESR1GPR35 | |
| SCHEMBL4845107 | 0.82 | GPR35 (0.39) | RAB9ANPC1GPR35MEN1KMT2A | |
| SCHEMBL15467799 | 0.81 | GPR35 (0.38) | RAB9ANPC1GPR35MEN1KMT2A | |
| SCHEMBL15471097 | 0.81 | GPR35 (0.38) | RAB9ANPC1GPR35MEN1KMT2A | |
| SCHEMBL15466436 | 0.79 | PGR (0.37) | RAB9ANPC1PGRGPR35POLB | |
| SCHEMBL15466437 | 0.79 | PGR (0.37) | RAB9ANPC1PGRGPR35POLB | |
| SCHEMBL15466438 | 0.79 | PGR (0.37) | RAB9ANPC1PGRGPR35POLB | |
| SCHEMBL4847049 | 0.79 | GPR35 (0.58) | ESR1GPR35MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365231-B2 | Compound with antitumor activity and preparation method therefor | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2008-04-29 | — | — | US | disclosed |
| US-20060241187-A1 | Compound with antitumor activity and preparation method therefor | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241187-A1 | Compound with antitumor activity and preparation method therefor | WEE1, WEE2, CYP51A1 | RAB9A 3978/4885NPC1 536/4885PGR 2516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.