Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3367027 | 0.82 | TAAR1 (0.50) | CA1CA9CA2TAAR1HDAC1 | |
| SCHEMBL1128268 | 0.82 | GAA (0.58) | CA1CA9CA2GAAMAPT | |
| SCHEMBL7896733 | 0.80 | GAA (0.43) | CA1CA9CA2TAAR1GAA | |
| SCHEMBL78688 | 0.75 | CA1 (0.54) | CA1CA9CA2ADRB2GAA | |
| SCHEMBL27434588 | 0.75 | TAAR1 (0.44) | CA1CA9CA2TAAR1ADRB2 | |
| SCHEMBL31248929 | 0.75 | TAAR1 (0.39) | CA1CA9CA2TAAR1CA12 | |
| SCHEMBL1639935 | 0.75 | CA1 (0.54) | CA1CA9CA2ADRB2GAA | |
| Hydrochloric Acid SCHEMBL7131081 | 0.73 | CA1 (0.52) | CA1CA9CA2ADRB2GAA | |
| Bromide SCHEMBL7131565 | 0.73 | CA1 (0.52) | CA1CA9CA2ADRB2GAA | |
| SCHEMBL23927494 | 0.71 | ALOX5 (0.39) | CA1CA9TAAR1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358397-B2 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2008-04-15 | — | — | US | claimed |
| US-20050143425-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2005-06-30 | — | — | US | claimed |
| CN-1616412-A | Process for the preparation of halogen containing 4-amino phenols | BAYER CHEMICALS AG (DE) | 2005-05-18 | — | — | CN | claimed |
| EP-1514865-A1 | Process for the preparation of halogen containing 4-amino phenols | Bayer Chemicals AG (DE) | 2005-03-16 | — | — | EP | claimed |
| US-20080139795-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2008-06-12 | — | — | US | disclosed |
| US-7358397-B2 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2008-04-15 | — | — | US | disclosed |
| US-20050143425-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2005-06-30 | — | — | US | disclosed |
| CN-1616412-A | Process for the preparation of halogen containing 4-amino phenols | BAYER CHEMICALS AG (DE) | 2005-05-18 | — | — | CN | disclosed |
| EP-1514865-A1 | Process for the preparation of halogen containing 4-amino phenols | Bayer Chemicals AG (DE) | 2005-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139795-A1 | Preparation of halogenated 4-aminophenols | CYP4X1, CYP4B1, PAH | CA1 4498/4885CA9 3160/4885CA2 3712/4885 |
| US-20050143425-A1 | Preparation of halogenated 4-aminophenols | CYP4X1, HPD, CYP4F8 | CA1 4576/4885CA9 2664/4885CA2 3410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.