Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL484379

COc1ncccc1C(N)=O.O=C(O)C(F)(F)F

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.49
L3MBTL1 Q9Y468 3/20 0.46
TDP1 Q9NUW8 1/20 0.43
SLC13A5 Q86YT5 1/20 0.43
PARP1 P09874 1/20 0.43
MAPT P10636 4/20 0.43
GAA P10253 1/20 0.43
ALDH1A1 P00352 4/20 0.41
HTT P42858 2/20 0.41
KDM4E B2RXH2 2/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
BLM P54132 1/20 0.40
AGER Q15109 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
NPC1 O15118 2/20 0.40
AHR P35869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL29810625 1.00 RAB9A (0.49) RAB9AL3MBTL1TDP1SLC13A5PARP1
SCHEMBL29980732 0.89 RAB9A (0.58) RAB9ATDP1PARP1MAPTGAA
SCHEMBL1723847 0.89 RAB9A (0.58) RAB9ATDP1PARP1MAPTGAA
Methane SCHEMBL25344317 0.88 RAB9A (0.56) RAB9ATDP1PARP1MAPTGAA
Hydrochloric Acid SCHEMBL16797856 0.88 RAB9A (0.56) RAB9ATDP1PARP1MAPTGAA
Formic Acid SCHEMBL9954308 0.83 RAB9A (0.52) RAB9ATDP1PARP1MAPTGAA
SCHEMBL20916924 0.80 RAB9A (0.55) RAB9APARP1MAPTALDH1A1HTT
SCHEMBL29477666 0.80 RAB9A (0.55) RAB9APARP1MAPTALDH1A1HTT
SCHEMBL29786037 0.78 RAB9A (0.54) RAB9ATDP1PARP1MAPTALDH1A1
SCHEMBL15664782 0.78 RAB9A (0.54) RAB9ATDP1PARP1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024067302-A1 AMIDE COMPOUND AND USE THEREOF IN PREPARATION OF INHIBITOR OF SIGMA2 AND 5HT2A 瀚远医药有限公司 2024-04-04 WO disclosed
EP-2411376-A1 INHIBITORS OF NF-KB Profectus Biosciences, Inc. (US) 2012-02-01 EP disclosed