Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20916924 | 1.00 | RAB9A (0.55) | RAB9ATYK2PARP1DHODHROCK2 | |
| SCHEMBL5529298 | 0.87 | RAB9A (0.68) | RAB9ADHODHROCK2KDM4EALDH1A1 | |
| SCHEMBL5534834 | 0.85 | RAB9A (0.52) | RAB9ATYK2ROCK2ALDH1A1 | |
| SCHEMBL30087468 | 0.84 | DHODH (0.57) | DHODHMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL2301749 | 0.84 | DHODH (0.57) | DHODHMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL5518570 | 0.83 | RAB9A (0.56) | RAB9ATYK2ROCK2KDM4EALDH1A1 | |
| SCHEMBL2798003 | 0.83 | DHODH (0.40) | RAB9ATYK2PARP1DHODHROCK2 | |
| SCHEMBL29686939 | 0.82 | RAB9A (0.51) | RAB9APARP1ROCK2KDM4EALDH1A1 | |
| SCHEMBL4263055 | 0.82 | RAB9A (0.51) | RAB9APARP1ROCK2KDM4EALDH1A1 | |
| SCHEMBL27313359 | 0.80 | TDP1 (0.61) | DHODHMAPTHTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12304907-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| US-20240279219-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-08-22 | — | — | US | disclosed |
| US-20230113778-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-04-13 | — | — | US | disclosed |
| US-11492350-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2022-11-08 | — | — | US | disclosed |
| US-20220127256-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279219-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | RAB9A 320/4885TYK2 2864/4885PARP1 2189/4885 |
| US-11492350-B2 | Compounds and methods of use | F12, C1R, ABCG2 | RAB9A 320/4885TYK2 2864/4885PARP1 2189/4885 |
| US-20230113778-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | RAB9A 320/4885TYK2 2864/4885PARP1 2189/4885 |
| US-12304907-B2 | Compounds and methods of use | F12, C1R, ABCG2 | RAB9A 320/4885TYK2 2864/4885PARP1 2189/4885 |
| US-20220127256-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | RAB9A 320/4885TYK2 2864/4885PARP1 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.