Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3585000 | 0.86 | NPSR1 (0.64) | NPSR1GFERMAPTALDH1A1KDM4E | |
| SCHEMBL3596620 | 0.83 | NPSR1 (0.62) | NPSR1GFERMAPTALDH1A1KDM4E | |
| SCHEMBL3592646 | 0.81 | NPSR1 (0.61) | NPSR1GFERMAPTALDH1A1KDM4E | |
| SCHEMBL3589035 | 0.80 | NPSR1 (0.67) | NPSR1GFERMAPTALDH1A1KDM4E | |
| SCHEMBL14160296 | 0.77 | ALDH1A1 (0.51) | NPSR1GFERMAPTALDH1A1KDM4E | |
| SCHEMBL14160376 | 0.76 | NPSR1 (0.52) | NPSR1GFERMAPTALDH1A1KDM4E | |
| SCHEMBL4795285 | 0.73 | NPSR1 (0.49) | NPSR1GFERMAPTALDH1A1KDM4E | |
| SCHEMBL3597401 | 0.73 | NPSR1 (0.55) | NPSR1GFERMAPTALDH1A1KDM4E | |
| SCHEMBL3576658 | 0.73 | NPSR1 (0.55) | NPSR1GFERMAPTALDH1A1KDM4E | |
| SCHEMBL3581683 | 0.73 | PPARD (0.56) | NPSR1GFERMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007036730-A9 | THIOPHENE DERIVATIVES AS PPAR AGONISTS I | INPHARMATICA LTD (GB) | 2008-06-19 | — | — | WO | claimed |