Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28882986 | 0.87 | SMN1; SMN2 (0.57) | HTTSMN1; SMN2KMT2APKMHPGD | |
| SCHEMBL2525981 | 0.87 | ALDH1A1 (0.60) | HTTSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL4740663 | 0.87 | SMN1; SMN2 (0.76) | HTTSMN1; SMN2KMT2AP2RX7PKM | |
| Hydrochloric Acid SCHEMBL1373954 | 0.85 | SMN1; SMN2 (0.74) | HTTSMN1; SMN2KMT2AP2RX7PKM | |
| SCHEMBL15415933 | 0.83 | ALDH1A1 (0.64) | HTTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL13387703 | 0.83 | SMN1; SMN2 (0.59) | HTTSMN1; SMN2KMT2AP2RX7PKM | |
| SCHEMBL13379358 | 0.82 | SMN1; SMN2 (0.58) | HTTSMN1; SMN2KMT2AP2RX7PKM | |
| SCHEMBL6272090 | 0.82 | KMT2A (0.64) | HTTSMN1; SMN2KMT2AP2RX7PKM | |
| SCHEMBL20676018 | 0.80 | SMN1; SMN2 (0.85) | HTTSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL25022751 | 0.79 | SIRT1 (0.59) | HTTSMN1; SMN2KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869363-B | 5-membered and bicyclic heterocyclic amides as ROCK inhibitors | 百时美施贵宝公司 | 2024-01-05 | — | — | CN | claimed |
| CN-115697327-A | 5-oxo-pyrrolidine-3-carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115697327-A | 5-oxo-pyrrolidine-3-carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2023-02-03 | — | — | CN | disclosed |
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |
| EP-1179341-B1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LTD (JP) | 2005-11-09 | — | — | EP | disclosed |
| CN-1384743-A | Remedies or preventives for diseases in association with chemokines | TEIJIN LTD (JP) | 2002-12-11 | — | — | CN | disclosed |
| EP-1179341-A1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |