Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562343 | 1.00 | ACACB (0.39) | ACACBACACAFFAR1CPT2TDP1 | |
| SCHEMBL9734360 | 0.98 | ACACB (0.36) | ACACBACACA | |
| SCHEMBL7416905 | 0.86 | GRN (0.33) | — | |
| SCHEMBL8842576 | 0.82 | CA1 (0.35) | ACACBACACA | |
| SCHEMBL6525783 | 0.79 | ACACB (0.39) | ACACBACACAFFAR1CPT2TDP1 | |
| SCHEMBL28023415 | 0.78 | ACACB (0.40) | ACACBACACAFFAR1CPT2TDP1 | |
| SCHEMBL8842692 | 0.78 | CA1 (0.37) | — | |
| SCHEMBL28023526 | 0.78 | ACACB (0.40) | ACACBACACAFFAR1CPT2TDP1 | |
| SCHEMBL1477140 | 0.77 | ACACB (0.38) | ACACBACACAFFAR1CPT2TDP1 | |
| SCHEMBL26209030 | 0.77 | ACACB (0.38) | ACACBACACAFFAR1CPT2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345037-B2 | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders | NITROMED, INC. (US) | 2008-03-18 | — | — | US | disclosed |
| US-20070155781-A1 | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders | ARBOR PHARMACEUTICALS, LLC | 2007-07-05 | — | — | US | disclosed |
| US-7160920-B2 | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders | NITROMED, INC. (US) | 2007-01-09 | — | — | US | disclosed |
| US-20030199529-A1 | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders | ARBOR PHARMACEUTICALS, LLC | 2003-10-23 | — | — | US | disclosed |
| US-6022714-A | Methods for attachment of a polynucleotide to a preselected material | GENETICS INSTITUTE (US) | 2000-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155781-A1 | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders | EDNRA, NOS3, NOS1 | ACACB 3671/4885ACACA 3206/4885FFAR1 148/4885 |
| US-20030199529-A1 | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders | NOS3, NOS1, EDNRA | ACACB 3732/4885ACACA 3315/4885FFAR1 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.