Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 7/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4844815 | 0.91 | SPR (0.30) | SPR | |
| SCHEMBL2962458 | 0.89 | GAA (0.35) | HPGDSMN1; SMN2HTTRAB9ASPR | |
| SCHEMBL1573996 | 0.85 | SPR (0.35) | SPR | |
| SCHEMBL16242498 | 0.84 | HPGD (0.35) | HPGDSMN1; SMN2HTTRAB9A | |
| SCHEMBL1573805 | 0.81 | HRH3 (0.35) | SPR | |
| SCHEMBL1573736 | 0.77 | SPR (0.35) | HPGDSPR | |
| SCHEMBL16242496 | 0.76 | SPR (0.32) | HPGDSMN1; SMN2HTTRAB9ASPR | |
| SCHEMBL4833062 | 0.75 | PDE10A (0.35) | SPR | |
| SCHEMBL16242494 | 0.74 | TRPV1 (0.34) | HPGD | |
| SCHEMBL16242373 | 0.73 | HPGD (0.34) | HPGDSMN1; SMN2HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937648-B1 | DIACYL INDAZOL DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS | SANOFI SA (FR) | 2014-11-26 | — | — | EP | disclosed |
| EP-1937648-A1 | DIACYL INDAZOL DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS | sanofi-aventis (FR) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007042178-A1 | DIACYL INDAZOL DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS | SANOFI-AVENTIS (DE) | 2007-04-19 | — | — | WO | disclosed |