SCHEMBL48449

SCHEMBL48449

Fc1cc(S)c(F)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.37
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5126094 1.00 TRPV4 (0.37) TRPV4CES2CES1
SCHEMBL1970246 0.79 TRPV4 (0.36) TRPV4CES2CES1
SCHEMBL41646 0.75 CA1 (0.43) CES2CES1
SCHEMBL7702552 0.75 CA1 (0.43) CES2CES1
SCHEMBL9150114 0.75 TRPV4 (0.33) TRPV4
SCHEMBL25837944 0.75 TRPV4 (0.33) TRPV4
SCHEMBL1971461 0.73 TRPV4 (0.36) TRPV4CES2CES1
SCHEMBL6193509 0.73 CES2 (0.42) TRPV4CES2CES1
SCHEMBL12856843 0.72 TRPV4 (0.43) TRPV4
SCHEMBL12410617 0.72 TRPV4 (0.57) TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1013 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116583623-A Selective deposition of silicon and oxygen containing dielectric films on dielectrics 弗萨姆材料美国有限责任公司 2023-08-11 CN claimed
CN-107903891-A A kind of preparation method and application of copper nanocluster self-assembly 天津科技大学 2018-04-13 CN claimed
CN-105358541-B Chiral 4 benzodihydropyrone is formed using chiral pyrrolidine in the presence of phenol or thiophenol 帝斯曼知识产权资产管理有限公司 2017-11-03 CN claimed
CN-106833406-A A kind of high refractive index nano inorganic matter hydridization photovoltaic encapsulation material 杭州福斯特光伏材料股份有限公司 2017-06-13 CN claimed
US-8198378-B2 Aromatic organosulfur functionalized 1,4-cis polybutadiene KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2012-06-12 US claimed
CN-102391424-A Method for modifying styrene-butadiene-styrene (SBS) block copolymer UNIV SHANGHAI JIAOTONG 2012-03-28 CN claimed
US-20110136956-A1 1,4-CIS-POLYBUTADIENE FUNCTIONALIZED WITH ORGANOSULFUR COMPOUND FOR PREPARATION OF GOLF BALL CORE KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2011-06-09 US claimed
US-7888432-B2 Having center, cover, or intermediate layer including reaction product that includes resilient polymer component, free radical source, zinc dimethacrylate and halogenated organosulfur compound; improved coefficient of restitution and increased compression ACUSHNET COMPANY (US) 2011-02-15 US claimed
US-7655732-B2 Low compression, resilient golf balls with rubber core ACUSHNET COMPANY (US) 2010-02-02 US claimed
US-20090156751-A1 Aromatic Organosulfur Functionalized 1,4-cis Polybutadiene KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2009-06-18 US claimed
US-20030134955-A1 Polybutadiene rubber composition comprising a halogenated organosulfur compound or a metal salt thereof JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-07-17 US claimed
US-20030130396-A1 Golf ball cores comprising a halogenated organosulfur compound ACUSHNET COMPANY 2003-07-10 US claimed
US-20030119989-A1 Low compression, resilient golf balls with rubber core ACUSHNET COMPANY 2003-06-26 US claimed
US-20030114249-A1 Golf ball core compositions comprising unsaturated long chain organic acids and their salts JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-06-19 US claimed
US-20030064826-A1 Golf ball cores comprising a halogenated organosulfur compound JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-04-03 US claimed
US-20020098915-A1 Thin, thermoset, polyurethane-covered golf ball with a dual core JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2002-07-25 US claimed
EP-0756520-A4 THE USE OF BLOCKED TIN CATALYST SYSTEM ASHLAND INC (US) 1997-08-20 EP claimed
EP-0756520-A1 THE USE OF BLOCKED TIN CATALYST SYSTEM ASHLAND INC. (US) 1997-02-05 EP claimed
US-5478790-A Storage stable, curable polymeric coating mixtures with tin or bismuth catalyst complexes in non-reactive non-carbonyl carriers ASHLAND OIL, INC. (US) 1995-12-26 US claimed
WO-1995029007-A1 THE USE OF BLOCKED TIN CATALYST SYSTEM ASHLAND INC. (US) 1995-11-02 WO claimed