Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 15/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4902040 | 0.90 | NR1H2 (0.38) | NR1H2MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL4782325 | 0.87 | NR1H2 (0.48) | NR1H2MEN1KMT2ANR1H3 | |
| SCHEMBL4838056 | 0.81 | CA1 (0.45) | NR1H2MEN1KMT2ACA1CA2 | |
| SCHEMBL4845688 | 0.81 | NR1H2 (0.38) | NR1H2KMT2ANR1H3 | |
| SCHEMBL4781448 | 0.81 | NR1H2 (0.57) | NR1H2MEN1KMT2A | |
| SCHEMBL4844757 | 0.78 | TBXA2R (0.41) | NR1H2NR1H3 | |
| SCHEMBL4911955 | 0.78 | KDM4E (0.43) | NR1H2MEN1KMT2ANR1H3 | |
| SCHEMBL4900753 | 0.78 | KDM4E (0.43) | NR1H2MEN1KMT2ANR1H3 | |
| SCHEMBL4785715 | 0.77 | TBXA2R (0.40) | NR1H2 | |
| SCHEMBL4913354 | 0.77 | TBXA2R (0.39) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061006-A1 | SUBSTITUTED INDAN-2-YL, TETRAHYDRONAPHTHALEN-2-YL, OR DIHYDR0-2H-CHR0MEN-3-YL ARYLSULFONAMIDES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |