SCHEMBL4844988

SCHEMBL4844988

NCCOc1cccc(CC(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 2/20 0.56
TAAR1 Q96RJ0 1/20 0.52
PPARD Q03181 2/20 0.51
CYP4F2 P78329 1/20 0.51
CYP4A11 Q02928 1/20 0.51
CFD P00746 1/20 0.48
LTA4H P09960 2/20 0.47
NR1H3 Q13133 1/20 0.47
FFAR1 O14842 2/20 0.47
PTPN11 Q06124 1/20 0.46
PLA2G2A P14555 1/20 0.46
LTB4R Q15722 1/20 0.46
AKR1B1 P15121 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL25374543 0.98 PLA2G4B (0.55) PLA2G4BTAAR1PPARDCYP4F2CYP4A11
SCHEMBL31457813 0.91 PLA2G4B (0.61) PLA2G4BPPARDCYP4F2CYP4A11CFD
SCHEMBL30278809 0.90 PLA2G4B (0.62) PLA2G4BPPARDCYP4F2CYP4A11NR1H3
SCHEMBL25081992 0.90 PLA2G4B (0.62) PLA2G4BPPARDCYP4F2CYP4A11NR1H3
SCHEMBL31457802 0.89 PLA2G4B (0.63) PLA2G4BPPARDCYP4F2CYP4A11NR1H3
SCHEMBL31457850 0.89 PLA2G4B (0.63) PLA2G4BPPARDCYP4F2CYP4A11NR1H3
SCHEMBL31457781 0.89 PLA2G4B (0.63) PLA2G4BPPARDCYP4F2CYP4A11NR1H3
SCHEMBL31457788 0.89 PLA2G4B (0.63) PLA2G4BPPARDCYP4F2CYP4A11NR1H3
SCHEMBL25081989 0.88 PLA2G4B (0.64) PLA2G4BPPARDCYP4F2CYP4A11NR1H3
SCHEMBL25081990 0.88 PLA2G4B (0.68) PLA2G4BPPARDCYP4F2CYP4A11NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7465811-B2 Indoline compounds LABORATOIRES FOURNIER S.A. (FR) 2008-12-16 US disclosed
US-20080119465-A1 Novel Indoline Compounds LABORATORIES FOURNIER S.A. (FR) 2008-05-22 US disclosed
US-4179511-A Antibacterial 3-(5-tetrazolyl) penam compounds PFIZER INC. (US) 1979-12-18 US disclosed
US-4143039-A ANTIBACTERIAL 3-(5-TETRAZOLYL)PENAM COMPOUNDS PFIZER INC. (US) 1979-03-06 US disclosed
US-4115385-A PENICILLINS PFIZER INC. (US) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119465-A1 Novel Indoline Compounds GPR119, INSR, IRS1 PLA2G4B 2191/4885TAAR1 509/4885PPARD 258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.