Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5904812 | 0.80 | USP2 (0.41) | ALDH1A1 | |
| SCHEMBL4845325 | 0.77 | KDM1A (0.47) | KMT2AATMCYP2D6CYP2C19KDM4E | |
| SCHEMBL4852978 | 0.74 | LMNA (0.38) | CYP2D6CYP2C19KDM4ETSHRALDH1A1 | |
| SCHEMBL3988708 | 0.72 | BACE1 (0.50) | ALDH1A1 | |
| SCHEMBL6650216 | 0.72 | APP (0.43) | ALDH1A1GAA | |
| SCHEMBL6677560 | 0.72 | APP (0.43) | ALDH1A1GAA | |
| SCHEMBL16314604 | 0.72 | ATM (0.82) | KMT2AATMCYP2D6CYP2C19KDM4E | |
| Hydrochloric Acid SCHEMBL4808510 | 0.71 | BACE1 (0.49) | ALDH1A1 | |
| SCHEMBL10982797 | 0.71 | ATM (0.85) | KMT2AATMCYP2D6CYP2C19KDM4E | |
| SCHEMBL14020065 | 0.71 | ATM (0.85) | KMT2AATMCYP2D6CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | claimed |
| US-20060005322-A1 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | claimed |
| EP-1580185-A1 | Secondary n-Alkylhydroxylated p-Phenylendiamins, dye composition for keratin fibers containing them, processes and uses. | L'OREAL (FR) | 2005-09-28 | — | — | EP | claimed |
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060005322-A1 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | KRT18, CDC73, PRKDC | KMT2A 699/4885ATM 2076/4885CYP2D6 1126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.