Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | CASR | P41180 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5904812 | 0.81 | USP2 (0.41) | CASRALDH1A1USP2 | |
| SCHEMBL11789982 | 0.79 | SCN5A (0.43) | LMNAACHESCN5AMAOAMAPK1 | |
| SCHEMBL4850035 | 0.77 | BCL2 (0.39) | LMNAACHEHTTMAOAMAPK1 | |
| SCHEMBL11494231 | 0.75 | SCN5A (0.42) | LMNAACHESCN5AMAOAMAPK1 | |
| SCHEMBL11793095 | 0.75 | KDM4E (0.42) | LMNAMAPK1KDM4ERAB9ATSHR | |
| SCHEMBL4949096 | 0.74 | CYP3A4 (0.52) | LMNAACHESCN5AMAOAMAPK1 | |
| SCHEMBL13713957 | 0.74 | USP2 (0.55) | LMNAACHEHTTCYP1A2CYP3A4 | |
| SCHEMBL4845349 | 0.74 | KMT2A (0.46) | KDM4ETSHRALDH1A1CYP2C19CYP2D6 | |
| SCHEMBL6677560 | 0.73 | APP (0.43) | SCN5AMAOAABCB11CYP3A4ADRA2B | |
| SCHEMBL20228146 | 0.73 | USP2 (0.53) | LMNAACHECASRHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | claimed |
| US-20060005322-A1 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | claimed |
| EP-1580185-A1 | Secondary n-Alkylhydroxylated p-Phenylendiamins, dye composition for keratin fibers containing them, processes and uses. | L'OREAL (FR) | 2005-09-28 | — | — | EP | claimed |
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060005322-A1 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | KRT18, CDC73, PRKDC | LMNA 285/4885ACHE 1363/4885CASR 4758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.