Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | CDC25B | P30305 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | DUSP1 | P28562 | 2/20 | 0.47 |
| ▸ | CDC25A | P30304 | 2/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CGAS | Q8N884 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4845752 | 1.00 | PTPN1 (0.56) | PTPN1CDC25BMEN1KMT2AMAPK1 | |
| SCHEMBL4854035 | 0.80 | MEN1 (0.60) | PTPN1MEN1KMT2AALDH1A1 | |
| SCHEMBL4854031 | 0.80 | MEN1 (0.60) | PTPN1MEN1KMT2AALDH1A1 | |
| SCHEMBL716851 | 0.76 | PTGS2 (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL3392792 | 0.75 | CDC25B (0.52) | PTPN1CDC25BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4843689 | 0.75 | PPARG (0.46) | PTPN1CDC25BMEN1KMT2AMAPK1 | |
| SCHEMBL4843702 | 0.75 | PPARG (0.46) | PTPN1CDC25BMEN1KMT2AMAPK1 | |
| SCHEMBL3391174 | 0.73 | CDC25B (0.63) | PTPN1CDC25BMEN1KMT2AMAPK1 | |
| SCHEMBL3391181 | 0.73 | CDC25B (0.63) | PTPN1CDC25BMEN1KMT2AMAPK1 | |
| SCHEMBL3392581 | 0.72 | CDC25B (0.81) | PTPN1CDC25BMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368578-B2 | Five-membered heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-06 | — | — | US | disclosed |
| US-20060135578-A1 | Five-membered heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-06-22 | — | — | US | disclosed |
| EP-1541564-A1 | FIVE-MEMBERED HETEROCYCLIC COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135578-A1 | Five-membered heterocyclic compounds | GPR119, OR10J3, CYP11B1 | PTPN1 1274/4885CDC25B 4355/4885MEN1 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.