Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21896419 | 1.00 | MEN1 (0.35) | MEN1KMT2ASLC6A3PTGER4HPGD | |
| SCHEMBL9149904 | 1.00 | MEN1 (0.35) | MEN1KMT2ASLC6A3PTGER4HPGD | |
| SCHEMBL18600852 | 0.87 | MEN1 (0.35) | MEN1KMT2ASLC6A3PTGER4HPGD | |
| SCHEMBL23598081 | 0.84 | SLC1A3 (0.36) | MEN1KMT2ASLC6A3PTGER4HPGD | |
| SCHEMBL29273102 | 0.84 | SLC6A3 (0.42) | MEN1KMT2ASLC6A3PTGER4HPGD | |
| SCHEMBL4300724 | 0.83 | MEN1 (0.37) | MEN1KMT2ASLC6A3PTGER4HPGD | |
| SCHEMBL9044354 | 0.83 | MEN1 (0.37) | MEN1KMT2ASLC6A3PTGER4HPGD | |
| SCHEMBL9213202 | 0.83 | MEN1 (0.37) | MEN1KMT2ASLC6A3PTGER4HPGD | |
| SCHEMBL4300716 | 0.83 | MEN1 (0.37) | MEN1KMT2ASLC6A3PTGER4HPGD | |
| SCHEMBL4300719 | 0.83 | MEN1 (0.37) | MEN1KMT2ASLC6A3PTGER4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432087-B2 | Method for preparing (2S, 3R, 4S)-4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFQUE (FR) | 2008-10-07 | — | — | US | disclosed |
| EP-1268397-B1 | METHOD FOR PREPARING (2S,3R,4S)-4-HYDROXYISOLEUCINE AND ANALOGUES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2007-12-05 | — | — | EP | disclosed |
| US-20050079587-A1 | Method for preparing (2S, 3R, 4S) -4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE | 2005-04-14 | — | — | US | disclosed |
| US-20030219880-A1 | Method for preparing (2s,3r,4s)-4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2003-11-27 | — | — | US | disclosed |
| EP-1268397-A2 | METHOD FOR PREPARING (2S,3R,4S)-4-HYDROXYISOLEUCINE AND ANALOGUES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001072688-A2 | METHOD FOR PREPARING (2S,3R,4S)-4-HYDROXYISOLEUCINE AND ANALOGUES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2001-10-04 | — | — | WO | disclosed |