Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849889 | 0.89 | F2 (0.52) | C5AR1FFAR1PPARDMEN1KMT2A | |
| SCHEMBL1842000 | 0.84 | MEN1 (0.56) | FFAR1MEN1KMT2AMRGPRX4NR4A2 | |
| SCHEMBL7907804 | 0.81 | PARP10 (0.54) | C5AR1FFAR1PPARDMEN1KMT2A | |
| SCHEMBL31643437 | 0.81 | MEN1 (0.52) | FFAR1MEN1KMT2AMRGPRX4NR4A2 | |
| SCHEMBL22490923 | 0.80 | MEN1 (0.54) | MEN1KMT2AMRGPRX4NR4A2 | |
| SCHEMBL597702 | 0.79 | MEN1 (0.63) | FFAR1MEN1KMT2AMRGPRX4S1PR1 | |
| SCHEMBL4849892 | 0.79 | C5AR1 (0.44) | C5AR1FFAR1PPARDMEN1KMT2A | |
| SCHEMBL31644137 | 0.79 | MEN1 (0.50) | FFAR1MEN1KMT2AMRGPRX4NR4A2 | |
| SCHEMBL4851469 | 0.78 | MEN1 (0.49) | C5AR1FFAR1MEN1KMT2AMRGPRX4 | |
| SCHEMBL7911253 | 0.78 | PARP10 (0.56) | C5AR1FFAR1PPARDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-6635655-B1 | Agonists or antagonists of peroxisome proliferator-activated receptors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-10-21 | — | — | US | disclosed |
| EP-1177187-A1 | DI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064888-A1 | DI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |