Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.56 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.56 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907804 | 0.89 | PARP10 (0.54) | PARP10PARP15C5AR1MAOBFFAR1 | |
| SCHEMBL3962253 | 0.84 | MAOB (0.61) | PARP15MAOBFFAR4ALDH1A1KDM4E | |
| SCHEMBL7317868 | 0.84 | PARP10 (0.57) | PARP10PARP15C5AR1MAOBFFAR1 | |
| SCHEMBL21924287 | 0.82 | MAOB (0.58) | PARP15MAOBFFAR4ALDH1A1HPGD | |
| SCHEMBL3191667 | 0.82 | MAOB (0.58) | PARP10PARP15MAOBFFAR4ALDH1A1 | |
| SCHEMBL3201763 | 0.81 | MAOB (0.57) | MAOBFFAR4ALDH1A1KDM4EHPGD | |
| SCHEMBL1763456 | 0.81 | MAOB (0.57) | PARP10PARP15MAOBFFAR4ALDH1A1 | |
| SCHEMBL6769322 | 0.81 | ALDH1A1 (0.64) | PARP10PARP15SGMS2ALDH1A1TSHR | |
| SCHEMBL2964664 | 0.80 | PARP10 (0.60) | PARP10PARP15MAOBALDH1A1 | |
| SCHEMBL7907439 | 0.80 | MAOB (0.56) | MAOBFFAR1FFAR4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |