Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17720792 | 0.77 | HDAC4 (0.37) | HDAC4HDAC2HDAC8HDAC6CTSK | |
| SCHEMBL17049264 | 0.76 | HDAC4 (0.50) | HDAC4HDAC2HDAC8HDAC6CTSK | |
| Ammonia Solution, Strong SCHEMBL27732707 | 0.76 | HDAC4 (0.42) | HDAC4HDAC2HDAC8HDAC6CTSK | |
| SCHEMBL17717462 | 0.76 | HDAC4 (0.36) | HDAC4HDAC2HDAC8HDAC6CTSK | |
| SCHEMBL809748 | 0.72 | HDAC2 (0.57) | HDAC4HDAC2HDAC8HDAC6CTSK | |
| SCHEMBL8429199 | 0.72 | HDAC2 (0.55) | HDAC4HDAC2HDAC8HDAC6CTSK | |
| SCHEMBL18897326 | 0.71 | HDAC2 (0.47) | HDAC4HDAC2HDAC8HDAC6CTSK | |
| SCHEMBL29288037 | 0.71 | HDAC2 (0.47) | HDAC4HDAC2HDAC8HDAC6CTSK | |
| SCHEMBL1114176 | 0.71 | HDAC2 (0.43) | HDAC4HDAC2HDAC8HDAC6CTSK | |
| SCHEMBL4710137 | 0.71 | HDAC4 (0.55) | HDAC4HDAC2HDAC8HDAC6CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1955991-A2 | Preparation of organic compounds bearing a trifluoromethyl group on a quaternary carbon | Air Products and Chemicals, Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| US-20080188689-A1 | Preparation of organic compounds bearing a trifluoromethyl group on a quaternary carbon | VERSUM MATERIALS US, LLC | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188689-A1 | Preparation of organic compounds bearing a trifluoromethyl group on a quaternary carbon | AFF4, RFC4, SF3B3 | HDAC4 418/4885HDAC2 2246/4885HDAC8 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.