Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858716 | 0.96 | — | — | |
| Bromide SCHEMBL7059450 | 0.92 | — | — | |
| Iodide SCHEMBL5238169 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL3377721 | 0.64 | BCHE (0.32) | — | |
| Water SCHEMBL3117304 | 0.61 | HSPD1 (0.32) | — | |
| Bromide SCHEMBL27637995 | 0.61 | BCHE (0.35) | — | |
| Hydrochloric Acid SCHEMBL547128 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL17801685 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL31318352 | 0.58 | SLC22A2 (0.45) | — | |
| Hydrochloric Acid SCHEMBL9095331 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303351-B1 | A PROCESS FOR THE PREPARATION OF BIS(CHLOROMETHYL)DICHLOROSILANE AND BIS(CHLOROMETHYL)(ARYL)CHLOROSILANE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-10-09 | — | — | EP | claimed |
| EP-3303351-A1 | A PROCESS FOR THE PREPARATION OF BIS(CHLOROMETHYL)DICHLOROSILANE AND BIS(CHLOROMETHYL)(ARYL)CHLOROSILANE | Dow Global Technologies LLC (US) | 2018-04-11 | — | — | EP | claimed |
| WO-2016191441-A1 | A PROCESS FOR THE PREPARATION OF BIS(CHLOROMETHYL)DICHLOROSILANE AND BIS(CHLOROMETHYL)(ARYL)CHLOROSILANE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-12-01 | — | — | WO | claimed |
| EP-0662474-B1 | PROCESS FOR THE PREPARATION OF CHLOROPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2003-05-14 | — | — | EP | claimed |
| US-5675010-A | CHLORINATING UNSATURATED AMIDE IN PRESENCE OF A SUBSTITUTED FORMAMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-07 | — | — | US | claimed |
| US-5541332-A | Chloropyridinium chlorides and process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-30 | — | — | US | claimed |
| EP-0662474-A1 | Chloropyridiniumchlorides and process for their preparation | BAYER AG (DE) | 1995-07-12 | — | — | EP | claimed |
| JP-7242634-A | — | — | None | — | — | JP | disclosed |
| EP-3303351-B1 | A PROCESS FOR THE PREPARATION OF BIS(CHLOROMETHYL)DICHLOROSILANE AND BIS(CHLOROMETHYL)(ARYL)CHLOROSILANE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-10-09 | — | — | EP | disclosed |
| US-10167301-B2 | Process for the preparation of bis(chloromethyl)dichlorosilane and bis(chloromethyl)(aryl)chlorosilane | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-20180155369-A1 | A PROCESS FOR THE PREPARATION OF BIS(CHLOROMETHYL)DICHLOROSILANE AND BIS(CHLOROMETHYL)(ARYL)CHLOROSILANE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-06-07 | — | — | US | disclosed |
| EP-3303351-A1 | A PROCESS FOR THE PREPARATION OF BIS(CHLOROMETHYL)DICHLOROSILANE AND BIS(CHLOROMETHYL)(ARYL)CHLOROSILANE | Dow Global Technologies LLC (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016191441-A1 | A PROCESS FOR THE PREPARATION OF BIS(CHLOROMETHYL)DICHLOROSILANE AND BIS(CHLOROMETHYL)(ARYL)CHLOROSILANE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-12-01 | — | — | WO | disclosed |
| US-5541332-A | Chloropyridinium chlorides and process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-30 | — | — | US | disclosed |
| CN-1110967-A | Chloropyridinium chlorides and process for their preparation | BAYER AG (DE) | 1995-11-01 | — | — | CN | disclosed |
| CN-1110967-A | Chloropyridinium chlorides and process for their preparation | BAYER AG (DE) | 1995-11-01 | — | — | CN | disclosed |
| JP-H07242634-A | CHLOROPYRIDINIUM CHLORIDE AND ITS PRODUCTION | BAYER AG | 1995-09-19 | — | — | JP | disclosed |
| EP-0662474-A1 | Chloropyridiniumchlorides and process for their preparation | BAYER AG (DE) | 1995-07-12 | — | — | EP | disclosed |
| EP-0662474-A1 | Chloropyridiniumchlorides and process for their preparation | BAYER AG (DE) | 1995-07-12 | — | — | EP | disclosed |
| EP-0662474-A1 | Chloropyridiniumchlorides and process for their preparation | BAYER AG (DE) | 1995-07-12 | — | — | EP | disclosed |