Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 18/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL854260 | 0.86 | CCNT1 (0.43) | PTGER2CCNT1 | |
| SCHEMBL6697790 | 0.84 | CCNT1 (0.42) | PTGER2CCNT1 | |
| SCHEMBL3427899 | 0.82 | PDE5A (0.50) | PTGER2PDE5A | |
| SCHEMBL6720555 | 0.82 | CCNT1 (0.41) | PTGER2CCNT1 | |
| SCHEMBL6178813 | 0.80 | RAB9A (0.50) | CCNT1 | |
| SCHEMBL6696521 | 0.76 | ALDH1A1 (0.38) | CCNT1 | |
| SCHEMBL6178015 | 0.76 | CCNT1 (0.42) | CCNT1 | |
| SCHEMBL27457410 | 0.75 | PDE5A (0.49) | PDE5A | |
| SCHEMBL6175456 | 0.74 | CCNT1 (0.40) | PTGER2CCNT1 | |
| Acetic Acid SCHEMBL4671431 | 0.74 | FABP1 (0.43) | CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368566-B2 | Process and intermediates for preparing benzazepines | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-06 | — | — | US | disclosed |
| US-20060194786-A1 | Process and intermediates for preparing benzazepines | SMITHKLINE BEECHAM CORPORATION | 2006-08-31 | — | — | US | disclosed |
| CN-1114403-C | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2003-07-16 | — | — | CN | disclosed |
| CN-1238689-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-12-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194786-A1 | Process and intermediates for preparing benzazepines | CYP2E1, CYP1B1, CYP3A4 | PTGER2 1094/4885PDE5A 2065/4885CCNT1 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.