SCHEMBL4847136

SCHEMBL4847136

N#CCCC(O)(CCC#N)COCCO

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4846040 0.74 ALDH1A1 (0.32) MEN1KMT2AALDH1A1
SCHEMBL25195833 0.72 TSHR (0.44) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL11483270 0.72 TSHR (0.39) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL36394 0.71 TSHR (0.54) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL1251675 0.71 TSHR (0.38) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL2528538 0.71
Di(Hydroxyethyl)Ether SCHEMBL22440719 0.71 TSHR (0.56) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL4854212 0.71 ALDH1A1 (0.37) TSHRMEN1KMT2AALDH1A1
SCHEMBL11423510 0.71 TSHR (0.47) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL17520040 0.71 MEN1 (0.31) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4549620-A1 PROCESS FOR MAKING AMINES FROM NITRILE COMPOUNDS USING HYDROGEN HAVING LOW DEUTERIUM CONTENT PRODUCED WITH NON-FOSSIL ENERGY IN THE ABSENCE OF AMMONIA BASF SE (DE) 2025-05-07 EP claimed
EP-4549618-A1 PROCESS FOR MAKING AMINES FROM NITRILE COMPOUNDS USING HYDROGEN HAVING LOW DEUTERIUM CONTENT PRODUCED WITH NON-FOSSIL ENERGY BASF SE (DE) 2025-05-07 EP claimed
US-7399886-B2 Aminopropylation of alcohols in the presence of amide or ether solvents AIR PRODUCTS AND CHEMICALS, INC. 2008-07-15 US claimed
US-20050054872-A1 Aminopropylation of alcohols in the presence of amide or ether solvents AIR PRODUCTS AND CHEMICALS, INC. 2005-03-10 US claimed
EP-1512675-A1 Aminopropylation of alcohols in the presence of amide or ether solvents AIR PRODUCTS AND CHEMICALS, INC. (US) 2005-03-09 EP claimed
EP-1215196-B1 Selective reductive amination of nitriles AIR PROD & CHEM (US) 2004-05-12 EP claimed
EP-0913388-B1 Hydrogenation of nitriles to produce amines AIR PROD & CHEM (US) 2003-10-01 EP claimed
EP-1215196-A1 Selective reductive amination of nitriles AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-06-19 EP claimed
US-6399830-B1 USING CATALYST AIR PRODUCTS AND CHEMICALS, INC. 2002-06-04 US claimed
US-6248925-B1 REACTING A NITRILE WITH A PRIMARY OR SECONDARY AMINE EFFECTING CONVERSION OF THE NITRILE GROUP TO THE CORRESPONDING SECONDARY OR TERTIARY AMINE; PROMOTIONALLY EFFECTIVE AMOUNT OF A LITHIUM COMPOUND OR SODIUM CHLORIDE. AIR PRODUCTS AND CHEMICALS, INC. 2001-06-19 US claimed
EP-0913388-A1 Hydrogenation of nitriles to produce amines AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-05-06 EP claimed
US-5869653-A USING SPONGE OR RANEY COBALT CATALYST; AMMONIA-FREE REACTION AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-02-09 US claimed
US-4313004-A CATALYTIC HYDROGENATION, BY-PRODUCT INHIBITION MILLIKEN RESEARCH CORPORATION (US) 1982-01-26 US claimed
EP-4549618-A1 PROCESS FOR MAKING AMINES FROM NITRILE COMPOUNDS USING HYDROGEN HAVING LOW DEUTERIUM CONTENT PRODUCED WITH NON-FOSSIL ENERGY BASF SE (DE) 2025-05-07 EP disclosed
EP-4549620-A1 PROCESS FOR MAKING AMINES FROM NITRILE COMPOUNDS USING HYDROGEN HAVING LOW DEUTERIUM CONTENT PRODUCED WITH NON-FOSSIL ENERGY IN THE ABSENCE OF AMMONIA BASF SE (DE) 2025-05-07 EP disclosed
US-7399886-B2 Aminopropylation of alcohols in the presence of amide or ether solvents AIR PRODUCTS AND CHEMICALS, INC. 2008-07-15 US disclosed
EP-1094058-A1 Selective reductive amination of nitriles AIR PRODUCTS AND CHEMICALS, INC. (US) 2001-04-25 EP disclosed
EP-0913388-A1 Hydrogenation of nitriles to produce amines AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-05-06 EP disclosed
US-5869653-A USING SPONGE OR RANEY COBALT CATALYST; AMMONIA-FREE REACTION AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-02-09 US disclosed
US-4313004-A CATALYTIC HYDROGENATION, BY-PRODUCT INHIBITION MILLIKEN RESEARCH CORPORATION (US) 1982-01-26 US disclosed