SCHEMBL4847168

SCHEMBL4847168

Nc1ccc(-c2c(N)c(N)c(N)c(N)c2N)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.59
ALDH1A1 P00352 6/20 0.59
TDP1 Q9NUW8 5/20 0.59
TP53 P04637 2/20 0.59
MEN1 O00255 3/20 0.50
MAPT P10636 3/20 0.50
KMT2A Q03164 3/20 0.50
HSD17B10 Q99714 3/20 0.48
TAAR1 Q96RJ0 2/20 0.48
APP P05067 2/20 0.43
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
ACHE P22303 2/20 0.40
KIF11 P52732 1/20 0.40
CA14 Q9ULX7 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9821744 0.85 CYP3A4 (0.56) CYP3A4ALDH1A1TDP1TP53MEN1
SCHEMBL6020612 0.84 CYP3A4 (0.62) CYP3A4ALDH1A1TDP1TP53MEN1
SCHEMBL9330651 0.81 CYP3A4 (0.59) CYP3A4ALDH1A1TDP1TP53MEN1
SCHEMBL4294687 0.76 TDP1 (0.46) CYP3A4ALDH1A1TDP1TP53MEN1
SCHEMBL2024128 0.75 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53MEN1
SCHEMBL258287 0.75 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53MEN1
Benzidine SCHEMBL5140469 0.75 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53MEN1
Benzidine SCHEMBL29021 0.75 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53MEN1
Benzidine SCHEMBL720393 0.75 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53MEN1
SCHEMBL17541403 0.75 CYP3A4 (0.59) CYP3A4ALDH1A1TDP1TP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113773491-A Polybenzimidazole derivative and application thereof in field of fluorescent probes 华南师范大学 2021-12-10 CN claimed
US-7396778-B2 Method for synthesizing polymeric material, method for forming polymer thin film and method for forming interlayer insulating film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2008-07-08 US claimed
US-20050245097-A1 Method for synthesizing polymeric material, method for forming polymer thin film and method for forming interlayer insulating film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-11-03 US claimed
US-6936552-B2 Method for synthesizing polymeric material, method for forming polymer thin film and method for forming interlayer insulating film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-08-30 US claimed
EP-1493771-A1 METHOD OF SYNTHESIZING POLYMERIC MATERIAL, METHOD OF FORMING THIN POLYMER FILM, AND METHOD OF FORMING INTERLAYER DIELECTRIC MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-01-05 EP claimed
US-20040087182-A1 Method for synthesizing polymeric material, method for forming polymer thin film and method for forming interlayer insulating film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD 2004-05-06 US claimed
CN-113773491-B Polybenzimidazole derivative and application thereof in fluorescent probe field 华南师范大学 2023-08-01 CN disclosed
CN-111001822-B Preparation method and application of multifunctional copper nanocluster 南华大学 2022-12-27 CN disclosed
CN-110724262-B Ternary light-resistant liquid crystal copolymer containing oxazole structure and preparation and application thereof 盐城瑞鼎科技有限公司 2022-05-13 CN disclosed
CN-113773491-A Polybenzimidazole derivative and application thereof in field of fluorescent probes 华南师范大学 2021-12-10 CN disclosed
CN-107007829-B Pneumonia multivalent conjugate vaccine and preparation method thereof 武汉博沃生物科技有限公司 2020-08-11 CN disclosed
CN-107412764-B Pneumococcal conjugate vaccine and preparation method thereof 武汉博沃生物科技有限公司 2020-08-11 CN disclosed
CN-105963691-B Streptococcus pneumoniae vaccine 查文娟 2020-05-01 CN disclosed
EP-1493771-A1 METHOD OF SYNTHESIZING POLYMERIC MATERIAL, METHOD OF FORMING THIN POLYMER FILM, AND METHOD OF FORMING INTERLAYER DIELECTRIC MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-01-05 EP disclosed
US-20040248223-A1 Reduction of interfering peroxidase activity in peroxidase based detection methods IDEXX LABORATORIES, INC. 2004-12-09 US disclosed
US-20040087182-A1 Method for synthesizing polymeric material, method for forming polymer thin film and method for forming interlayer insulating film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD 2004-05-06 US disclosed
EP-0232829-B1 Process for forming a film of a polymer. KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-05-05 EP disclosed
US-4910293-A Amphiphilic high polymer KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-03-20 US disclosed
EP-0232829-A2 Process for forming a film of a polymer. KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-08-19 EP disclosed
EP-0230539-A2 Amphiphilic high polymer and process for producing the same KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245097-A1 Method for synthesizing polymeric material, method for forming polymer thin film and method for forming interlayer insulating film PARG, STOM, DNMT1 CYP3A4 4350/4885ALDH1A1 3073/4885TDP1 1734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.