Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991776 | 0.81 | ALDH1A1 (0.41) | TDP1CYP3A4ALDH1A1TAAR1HSD17B10 | |
| SCHEMBL7515231 | 0.80 | CYP3A4 (0.40) | TDP1CYP3A4ALDH1A1TP53TAAR1 | |
| SCHEMBL4847168 | 0.76 | CYP3A4 (0.59) | TDP1CYP3A4ALDH1A1TP53TAAR1 | |
| SCHEMBL6020612 | 0.73 | CYP3A4 (0.62) | TDP1CYP3A4ALDH1A1TP53TAAR1 | |
| SCHEMBL29450595 | 0.73 | CYP3A4 (0.71) | TDP1CYP3A4ALDH1A1TP53TAAR1 | |
| SCHEMBL969462 | 0.72 | ALDH1A1 (0.61) | TDP1CYP3A4ALDH1A1TP53TAAR1 | |
| SCHEMBL4294691 | 0.71 | TDP1 (0.46) | TDP1CYP3A4ALDH1A1TP53TAAR1 | |
| SCHEMBL9330651 | 0.71 | CYP3A4 (0.59) | TDP1CYP3A4ALDH1A1TP53TAAR1 | |
| Benzidine SCHEMBL8836043 | 0.71 | CYP3A4 (0.69) | TDP1CYP3A4ALDH1A1TP53TAAR1 | |
| SCHEMBL31327474 | 0.71 | CYP3A4 (0.59) | TDP1CYP3A4ALDH1A1TP53TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10080774-B2 | Oncolytic adenovirus armed with therapeutic genes | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-09-25 | — | — | US | disclosed |
| US-20150306160-A1 | ONCOLYTIC ADENOVIRUS ARMED WITH THERAPEUTIC GENES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-10-29 | — | — | US | disclosed |
| US-9061055-B2 | Oncolytic adenovirus armed with therapeutic genes | Board of Regentsm The University of Texas System (US) | 2015-06-23 | — | — | US | disclosed |
| US-20090175830-A1 | ONCOLYTIC ADENOVIRUS ARMED WITH THERAPEUTIC GENES | FUEYO JUAN | 2009-07-09 | — | — | US | disclosed |
| US-20060147420-A1 | Oncolytic adenovirus armed with therapeutic genes | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2006-07-06 | — | — | US | disclosed |
| WO-2005086922-A2 | ONCOLYTIC ADENOVIRUS ARMED WITH THERAPEUTIC GENES | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2005-09-22 | — | — | WO | disclosed |