Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4852725 | 1.00 | HTR6 (0.59) | HTR6CA2CA9MEN1KMT2A | |
| SCHEMBL947465 | 0.88 | HTR6 (0.59) | HTR6CA2CA9MEN1KMT2A | |
| SCHEMBL947467 | 0.88 | HTR6 (0.59) | HTR6CA2CA9MEN1KMT2A | |
| SCHEMBL946782 | 0.87 | HTR6 (0.57) | HTR6CA2CA9MEN1KMT2A | |
| SCHEMBL946781 | 0.87 | HTR6 (0.57) | HTR6CA2CA9MEN1KMT2A | |
| SCHEMBL28245176 | 0.86 | HTR6 (0.61) | HTR6CA2CA9MEN1KMT2A | |
| SCHEMBL947557 | 0.86 | KDM4E (0.61) | HTR6CA2CA9KDM4EUBE2N | |
| SCHEMBL947555 | 0.86 | KDM4E (0.61) | HTR6CA2CA9KDM4EUBE2N | |
| SCHEMBL947398 | 0.85 | HTR6 (0.59) | HTR6KDM4EUBE2NCYP19A1 | |
| SCHEMBL4776910 | 0.81 | HTR6 (0.63) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581492-B1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2008-07-16 | — | — | EP | disclosed |