Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 11/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | TNKS | O95271 | 6/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.56 |
| ▸ | PARP1 | P09874 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4579536 | 0.80 | GUSB (0.63) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL29890314 | 0.79 | GUSB (1.00) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL30259689 | 0.79 | GUSB (1.00) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL296097 | 0.79 | GUSB (1.00) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL6695759 | 0.78 | TNKS2 (0.81) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL28135155 | 0.77 | GUSB (0.69) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL13381565 | 0.77 | GUSB (0.68) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL2606253 | 0.76 | GUSB (0.68) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL802560 | 0.76 | GUSB (0.68) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL4712040 | 0.76 | GUSB (0.68) | GUSBHPGDKDM4ETNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348160-B2 | Phosphoamidase assay | MERCK PATENT GMBH (DE) | 2008-03-25 | — | — | US | claimed |
| US-7348160-B2 | Phosphoamidase assay | MERCK PATENT GMBH (DE) | 2008-03-25 | — | — | US | disclosed |
| EP-1468108-B1 | PHOSPHOAMIDASE ASSAY | MERCK PATENT GMBH (DE) | 2005-12-14 | — | — | EP | disclosed |
| US-20050124023-A1 | Phosphoamidase assay | MERCK PATENT GMBH (DE) | 2005-06-09 | — | — | US | disclosed |
| EP-1468108-A1 | PHOSPHOAMIDASE ASSAY | MERCK PATENT GmbH (DE) | 2004-10-20 | — | — | EP | disclosed |
| WO-2004044233-A1 | PHOSPHOAMIDASE ASSAY | MERCK PATENT GMBH (DE) | 2004-05-27 | — | — | WO | disclosed |