Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 11/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TNKS | O95271 | 3/20 | 0.52 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.52 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188092 | 0.86 | GUSB (0.47) | GUSBHPGDKDM4ECYP1A1CYP1B1 | |
| Ammonia Solution, Strong SCHEMBL2685962 | 0.85 | GUSB (0.46) | GUSBHPGDKDM4ECYP1A1CYP1B1 | |
| SCHEMBL4579539 | 0.82 | GUSB (0.67) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL1084872 | 0.81 | GUSB (0.78) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL29740691 | 0.81 | GUSB (0.78) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL13604403 | 0.81 | GUSB (0.69) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL4847440 | 0.80 | GUSB (0.65) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL297069 | 0.79 | GUSB (0.67) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL14845878 | 0.79 | GUSB (0.63) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL7160589 | 0.77 | GUSB (1.00) | GUSBHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140349893-A1 | LABELING OF IMMOBILIZED PROTEINS USING DIPYRROMETHENEBORON DIFLUORIDE DYES | Life Technologies Corporation (US) | 2014-11-27 | — | — | US | disclosed |
| US-20080182284-A1 | Labeling or detecting of immobilized poly(amino acids), including peptides, polypeptides and proteins, on membranes and other solid supports; | INVITROGEN CORPORATION (US) | 2008-07-31 | — | — | US | disclosed |
| US-7348160-B2 | Phosphoamidase assay | MERCK PATENT GMBH (DE) | 2008-03-25 | — | — | US | disclosed |
| US-7348160-B2 | Phosphoamidase assay | MERCK PATENT GMBH (DE) | 2008-03-25 | — | — | US | disclosed |
| US-20050287618-A1 | Labeling or detecting of immobilized poly(amino acids), including peptides, polypeptides and proteins, on membranes and other solid supports; | HAUGLAND RICHARD P | 2005-12-29 | — | — | US | disclosed |
| US-6972326-B2 | immobilized poly(amino acids) are labeled or detected on blots or on arrays of poly(amino acids), or are attached to immobilized aptamers; use in analysis and diagnostics | MOLECULAR PROBES, INC. (US) | 2005-12-06 | — | — | US | disclosed |
| US-20050186641-A1 | immobilized poly(amino acids) are labeled or detected on blots or on arrays of poly(amino acids), or are attached to immobilized aptamers; use in analysis and diagnostics | MOLECULAR PROBES, INC. (US) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050186641-A1 | immobilized poly(amino acids) are labeled or detected on blots or on arrays of poly(amino acids), or are attached to immobilized aptamers; use in analysis and diagnostics | PARN, DNPEP, PUF60 | GUSB 3651/4885HPGD 4684/4885KDM4E 4169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.