SCHEMBL4847740

SCHEMBL4847740

C1=Cc2c3ccc4c5ccccc5ccc4c3cc3cccc1c23

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.47
CYP1A2 P05177 5/20 0.44
FYN P06241 2/20 0.44
ACHE P22303 2/20 0.44
AHR P35869 2/20 0.44
ERBB2 P04626 1/20 0.44
MAOA P21397 1/20 0.44
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 3/20 0.44
HIF1A Q16665 2/20 0.44
CYP1B1 Q16678 1/20 0.44
LCK P06239 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
MAPT P10636 1/20 0.42
SLC6A2 P23975 1/20 0.42
TDP1 Q9NUW8 2/20 0.40
CYP2A6 P11509 1/20 0.40
TSHR P16473 1/20 0.40
HPGD P15428 2/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[J]Aceanthrylene SCHEMBL1289323 0.98 CYP1A2 (0.46) HPRT1CYP1A2FYNACHEAHR
SCHEMBL4846775 0.89 CYP1A2 (0.43) HPRT1CYP1A2FYNACHEAHR
SCHEMBL4853798 0.87 CYP1A2 (0.44) HPRT1CYP1A2FYNACHEAHR
SCHEMBL4850326 0.85 ALDH1A1 (0.52) HPRT1CYP1A2FYNACHEAHR
SCHEMBL4853363 0.84 CYP1A2 (0.44) HPRT1CYP1A2FYNACHEAHR
SCHEMBL4845200 0.82 ALDH1A1 (0.45) HPRT1CYP1A2FYNACHEAHR
Triphenylene SCHEMBL22493025 0.82 CYP1A2 (0.46) HPRT1CYP1A2FYNACHEAHR
SCHEMBL4852228 0.82 ALDH1A1 (0.49) HPRT1CYP1A2FYNACHEAHR
SCHEMBL4852131 0.81 HSD17B10 (0.50) HPRT1CYP1A2FYNACHEAHR
SCHEMBL4851870 0.81 HPRT1 (0.52) HPRT1CYP1A2FYNACHEAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed