SCHEMBL4852228

SCHEMBL4852228

C1=Cc2c3cc4c(ccc5ccccc54)cc3cc3cccc1c23

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
HSD17B10 Q99714 5/20 0.49
CYP1A2 P05177 4/20 0.49
HPGD P15428 4/20 0.49
ERBB2 P04626 1/20 0.47
FYN P06241 1/20 0.47
MAOA P21397 1/20 0.47
ACHE P22303 1/20 0.47
AHR P35869 1/20 0.47
HIF1A Q16665 2/20 0.47
CYP1B1 Q16678 2/20 0.47
TSHR P16473 2/20 0.39
CYP2A6 P11509 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPRT1 P00492 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NQO2 P16083 2/20 0.36
P2RX4 Q99571 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4850326 0.97 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP1A2HPGDERBB2
SCHEMBL26028 0.86 CYP1A2 (0.47) ALDH1A1HSD17B10CYP1A2HPGDERBB2
SCHEMBL29562021 0.86 CYP1A2 (0.47) ALDH1A1HSD17B10CYP1A2HPGDERBB2
Triphenylene SCHEMBL22493025 0.84 CYP1A2 (0.46) ALDH1A1HSD17B10CYP1A2HPGDERBB2
SCHEMBL4848697 0.84 CYP1A2 (0.37) ALDH1A1HSD17B10CYP1A2HPGDERBB2
SCHEMBL4853146 0.83 ALDH1A1 (0.51) ALDH1A1HSD17B10CYP1A2HPGDERBB2
Benzo[J]Aceanthrylene SCHEMBL1289323 0.83 CYP1A2 (0.46) ALDH1A1HSD17B10CYP1A2HPGDERBB2
SCHEMBL4851840 0.83 CYP1A2 (0.36) ALDH1A1HSD17B10CYP1A2HPGDERBB2
SCHEMBL4853363 0.83 CYP1A2 (0.44) ALDH1A1HSD17B10CYP1A2HPGDERBB2
SCHEMBL4847740 0.82 HPRT1 (0.47) ALDH1A1HSD17B10CYP1A2HPGDERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed