Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900885 | 0.87 | KMT2A (0.44) | ALDH1A1DRD1KMT2ASMN1; SMN2HTT | |
| SCHEMBL900624 | 0.85 | ALDH1A1 (0.49) | ALDH1A1DRD1KMT2ASMN1; SMN2HTT | |
| SCHEMBL4654255 | 0.78 | DRD1 (0.48) | ALDH1A1DRD1KMT2ASMN1; SMN2HTT | |
| SCHEMBL885349 | 0.78 | DRD1 (0.42) | ALDH1A1DRD1KMT2ASMN1; SMN2HTT | |
| SCHEMBL12474316 | 0.78 | KMT2A (0.37) | ALDH1A1DRD1KMT2ASMN1; SMN2HTT | |
| SCHEMBL16955000 | 0.76 | DRD1 (0.34) | ALDH1A1DRD1KMT2ASMN1; SMN2HTT | |
| SCHEMBL900289 | 0.76 | ALDH1A1 (0.42) | ALDH1A1DRD1KMT2ASMN1; SMN2HTT | |
| SCHEMBL16950831 | 0.76 | KMT2A (0.35) | ALDH1A1DRD1KMT2ASMN1; SMN2HTT | |
| SCHEMBL18257237 | 0.75 | DRD1 (0.39) | ALDH1A1DRD1KMT2ASMN1; SMN2HTT | |
| SCHEMBL19573862 | 0.75 | SMN1; SMN2 (0.40) | ALDH1A1DRD1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368463-B2 | Substituted 4-amino-1-benzylpiperidine compounds | THERAVANCE, INC. (US) | 2008-05-06 | — | — | US | disclosed |