Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31204098 | 0.98 | ALDH1A1 (0.77) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Iodide SCHEMBL9185304 | 0.96 | ALDH1A1 (0.74) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL4881713 | 0.96 | ALDH1A1 (0.74) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL163452 | 0.94 | ALDH1A1 (0.71) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL2854923 | 0.92 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL5573865 | 0.92 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL1449856 | 0.92 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL3437057 | 0.92 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL20541362 | 0.92 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Bromide SCHEMBL711677 | 0.92 | TSHR (0.69) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120005305-A | Polyethylene composite packaging material containing modified graphene and preparation method thereof | 滨州万佳新材料有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119978777-A | Modified 6-chloro-1H-pyrazolo [4,3-C ] pyridine-alcohol-containing material and preparation method thereof | 苏州求索生物科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119931676-A | Carbon-based soil modifier and preparation method thereof | 烟台华伊绿能科技有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119823520-A | Antibacterial ABS material and preparation method thereof | 山东颐工材料科技股份有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119709179-A | Preparation method of mitochondrion targeting fluorescent probe and application of mitochondrion targeting fluorescent probe in biological imaging | 浙江省中医药研究院 | 2025-03-28 | — | — | CN | claimed |
| CN-119431924-A | Polymer antibacterial material and preparation method thereof | 昆山复纳材料科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-118561455-A | Treatment process of p-nitrochlorobenzene waste water | 安徽东至广信农化有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-115960361-A | pHLIP-PEI-TPP copolymer, drug delivery carrier and application thereof | 山西大学 | 2023-04-14 | — | — | CN | claimed |
| CN-114681426-B | Probiotics polymer microcapsule preparation and preparation method and application thereof | 珠海横琴澳叶健康科技有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-115708876-A | Light-sensitive carrier material with mitochondrion targeting function and preparation method and application thereof | 温州大学 | 2023-02-24 | — | — | CN | claimed |
| CN-113321747-A | Antibacterial component containing quaternary phosphonium salt modified locust bean gum | 广州市尚信净化工程有限公司 | 2021-08-31 | — | — | CN | claimed |
| CN-112587503-A | Stimulus-response astaxanthin nanoparticle, preparation method thereof and application of nanoparticle in mitochondrial targeting and colon inflammation relieving direction | 大连工业大学 | 2021-04-02 | — | — | CN | claimed |
| WO-2021031321-A1 | MULTI-COLOR UP-CONVERSION NANOPROBE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 青岛大学 | 2021-02-25 | — | — | WO | claimed |
| CN-112358867-A | Quantum dot-based mitochondrial fluorescent probe and preparation method and application thereof | 河南大学 | 2021-02-12 | — | — | CN | claimed |
| WO-2021018099-A1 | H2O2-RESPONSIVE CROSSLINKING NEAR-INFRARED MOLECULAR PROBE FOR TUMOR MICROENVIRONMENT AND USE THEREFOR | 苏州大学 | 2021-02-04 | — | — | WO | claimed |
| CN-111876144-A | Nano triphenylphosphine MoS for targeting mitochondria2Synthesis method of quantum dots | 南开大学 | 2020-11-03 | — | — | CN | claimed |
| CN-110407873-B | Tumor microenvironment H2O2Response crosslinking near-infrared molecular probe and application thereof | 苏州大学 | 2020-10-16 | — | — | CN | claimed |
| EP-3699167-A1 | PROCESS FOR PREPARING METHYL 1-BENZOSUBERONE-7-CARBOXYLATE | Sanofi (FR) | 2020-08-26 | — | — | EP | claimed |
| CN-107200788-B | Quaternary phosphonium chitosan and application thereof as vaccine immunologic adjuvant | 暨南大学 | 2020-04-14 | — | — | CN | claimed |
| CN-110613855-A | Nano-gold-plugged mesoporous silicon drug controlled release system | 湖北大学 | 2019-12-27 | — | — | CN | claimed |