SCHEMBL4848098

SCHEMBL4848098

COP(=O)(F)C(C)C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSA P10619 1/20 0.35
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61141 0.73
SCHEMBL12225572 0.70 CTSA (0.33) CTSAACHE
SCHEMBL2568255 0.68 CTSA (0.44) CTSAACHE
SCHEMBL11794084 0.67 CYP2C19 (0.35)
SCHEMBL11795142 0.65 LAP3 (0.33)
SCHEMBL2991395 0.63 TP53 (0.33) CTSAACHE
SCHEMBL6831886 0.61 LAP3 (0.46)
SCHEMBL575328 0.61
Soman SCHEMBL3796733 0.60 CTSA (0.40) CTSAACHE
SCHEMBL5061038 0.60 CTSA (0.46) CTSAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7468672-B2 Detection and identification method for in-transit determination of chemical contraband, decaying animal and vegetable matter, and concealed humans in cargo shipping containers and other secure spaces Harden, Charles S. (US) 2008-12-23 US disclosed
US-20070277589-A1 Detection and identification method for in-transit determination of chemical contraband, decaying animal and vegetable matter, and concealed humans in cargo shipping containers and other secure spaces HARDEN CHARLES S 2007-12-06 US disclosed
US-20070093518-A1 Pharmaceutical compositions for the treatment of organophosphate poisoning SECRETARY OF STATE FOR DEFENCE, THE (GB) 2007-04-26 US disclosed
EP-1663203-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ORGANOPHOSPHATE POISONING The Secretary of State for Defence (GB) 2006-06-07 EP disclosed
US-6960701-B2 Neutralization of vesicants and related compounds EAI CORPORATION (US) 2005-11-01 US disclosed
WO-2005027905-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ORGANOPHOSPHATE POISONING THE SECRETARY OF STATE FOR DEFENCE (GB) 2005-03-31 WO disclosed
US-6722182-B1 Solid state vapor generator THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2004-04-20 US disclosed
WO-2003097173-A1 NEUTRALIZATION OF VESICANTS AND RELATED COMPOUNDS EAI CORPORATION (US) 2003-11-27 WO disclosed
US-6570048-B1 Chemical warfare; oxidation using alkali persulfate compound COMMODORE APPLIED TECHNOLOGIES, INC. 2003-05-27 US disclosed
US-20030009074-A1 Neutralization of vesicants and related compounds LEIDOS, INC. 2003-01-09 US disclosed
WO-1998028045-A2 METHOD FOR DESTROYING ENERGETIC MATERIALS COMMODORE APPLIED TECHNOLOGIES, INC. (US) 1998-07-02 WO disclosed
WO-1997018858-A1 METHOD AND APPARATUS TO DESTROY CHEMICAL WARFARE AGENTS COMMODORE APPLIED TECHNOLOGIES, INC. (US) 1997-05-29 WO disclosed
US-5538641-A Process for recycling laden fluids GLOBAL ENVIRONMENTAL SOLUTIONS, INC. (US) 1996-07-23 US disclosed
WO-1996021838-A2 HIGH PRESSURE WASHOUT OF CHEMICAL AGENTS ALLIANT TECHSYSTEMS INC. (US) 1996-07-18 WO disclosed
WO-1996020904-A1 PROCESS FOR RECYCLING LADEN FLUIDS GLOBAL ENVIRONMENTAL SOLUTIONS, INC. (US) 1996-07-11 WO disclosed
US-5484728-A Parathion hydrolase analogs and methods for production and purification AMGEN INC. (US) 1996-01-16 US disclosed
EP-0394393-A4 PARATHION HYDROLASE ANALOGS AND METHODS FOR PRODUCTION AND PURIFICATION 1992-05-06 EP disclosed
EP-0398537-A1 Decontamination of toxic chemical agents DOW CORNING CORPORATION (US) 1990-11-22 EP disclosed
EP-0394393-A1 PARATHION HYDROLASE ANALOGS AND METHODS FOR PRODUCTION AND PURIFICATION AMGEN INC. (US) 1990-10-31 EP disclosed
WO-1990002177-A1 PARATHION HYDROLASE ANALOGS AND METHODS FOR PRODUCTION AND PURIFICATION AMGEN INC. (US) 1990-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070093518-A1 Pharmaceutical compositions for the treatment of organophosphate poisoning ACHE, CHRM3, BCHE CTSA 260/4885ACHE 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.